Results 171 to 180 of about 4,484,193 (288)

Parental Competencies as Familial Protective Factors in Adolescent Substance Use Prevention: A Scoping Review. [PDF]

Children (Basel)
Hong KY, Shin J.
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Bistable Networks Enable Complex Shape Changes. [PDF]

Adv Sci (Weinh)
Thomas S, Lipton J.
europepmc   +1 more source

On the planar development of classical developable surfaces

This paper presents a self-contained and explicit derivation of the planar development of regular developable surfaces, starting from the coefficients of the first fundamental form. Under the developability condition, the induced metric has a polynomial structure that allows one to construct explicitly a local isometry onto the plane.
openaire   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Characterising nanobody developability to improve therapeutic design using the Therapeutic Nanobody Profiler. [PDF]

Commun Biol
Gordon GL, Gervasio J, Souders C, Deane CM.   +3 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Rigid-flexible interlocked metastructures enable conformal stealth. [PDF]

Sci Adv
Sun C, Li D, Liao W, Liu T.
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

POSITION VECTOR OF A DEVELOPABLE &ITh&IT-SLANT RULED SURFACE

In physics and geometry, the determination of position vector of a moving point is an important problem, since the trajectory of that point is a curve or a surface which are important in physics, geometry, and applied sciences.
Önder, M, Kaya, O
core