Results 231 to 240 of about 5,553,659 (298)

A Scoping Review of Human Teratogens and Their Impact on the Developing Brain: A Contribution From the ConcePTION Project. [PDF]

Birth Defects Res
Bluett-Duncan M, Adams J, Berkovitch M, Berlin M, Cahoon A, Clayton-Smith J, Jackson C, Khanom S, Mølgaard-Nielsen D, Richardson JL, Simms V, Stellfeld M, Winterfeld U, Yates LM, Bromley RL.   +14 more
europepmc   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Safety of 810 nm photobiomodulation in the developing brain: no evidence of glial reactivity or pro-inflammatory cytokine expression in rats. [PDF]

Lasers Med Sci
Gutiérrez-Menéndez A, Rodríguez-Fernández L, Zorzo C, Martínez JA, Diez-Solinska A, Arias JL.   +5 more
europepmc   +1 more source

Vascular Disease, Non‐Steroidal Anti‐Inflammatory Drugs and Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Clare Wotton, Carol Hermon, Sarah Floud, Gillian Reeves, Isobel Barnes   +4 more
wiley   +1 more source

Age-Dependent Entropic Features During Propofol Anesthesia in Developing Brain. [PDF]

Anesth Analg
Zhang Y, Liang ZH, Wang X, Zhang N, Zhu HT, Wang DX, Guo XY, Li XL, Song LL.   +8 more
europepmc   +1 more source

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

Developing brain asymmetry shapes cognitive and psychiatric outcomes in adolescence. [PDF]

Nat Commun
Wu X, Zhang K, Kuang N, Kong X, Cao M, Lian Z, Liu Y, Fan H, Yu G, Liu Z, Cheng W, Jia T, Sahakian BJ, Robbins TW, Feng J, Schumann G, Palaniyappan L, Zhang J.   +17 more
europepmc   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Author Correction: Developing brain asymmetry shapes cognitive and psychiatric outcomes in adolescence. [PDF]

Nat Commun
Wu X, Zhang K, Kuang N, Kong X, Cao M, Lian Z, Liu Y, Fan H, Yu G, Liu Z, Cheng W, Jia T, Sahakian BJ, Robbins TW, Feng J, Schumann G, Palaniyappan L, Zhang J.   +17 more
europepmc   +1 more source

Mechanical stress connects cortical folding to fiber organization in the developing brain. [PDF]

Trends Neurosci
Garcia KE, Kroenke CD, Bayly PV.
europepmc   +1 more source