Results 251 to 260 of about 5,553,659 (298)

Brain development and generation of brain pathologies

2001
The timing of brain development is genetically programmed and can be profoundly altered by a number of abnormal genes that control proliferation, differentiation, migration, synapse formation, and elimination of cells and synapses. With advances in genetic techniques both the gene and gene product responsible for brain malformation are being identified
G L, Holmes, B, McCabe
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Reelin and brain development

Nature Reviews Neuroscience, 2003
Over the last 50 years, the reeler mutant mouse has become an important model for studying normal and abnormal development in the cerebral cortex and other regions of the brain. However, we are only just beginning to understand the actions of reelin — the protein that is affected by the reeler mutation — at the molecular and cellular level. This review
Fadel, Tissir, André M, Goffinet
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Brain Fuel Utilization in the Developing Brain

Annals of Nutrition and Metabolism, 2019
During pregnancy and infancy, the human brain is growing extremely fast; the brain volume increases significantly, reaching 36, 72, and 83% of the volume of adults at 2–4 weeks, 1 year, and 2 years of age, respectively, which is essential to establish the neuronal networks and capacity for the development of cognitive, motor, social, and emotional ...
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Iodine and brain development

BioFactors, 1999
AbstractThe development of the brain is critically dependent on an adequate supply of iodine. Iodine is an integral part of thyroid hormone, which acts on brain development by regulating the expression of target genes. The active thyroid hormone, T3, is generated in part in the thyroid gland, but about 80% of T3 in brain is formed locally from T4 ...
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On the Development of a Brain Simulator

2010
Developing a whole brain simulator, a computer simulation in modeling brain structure and functionality of human, is the ultimate goal of Brain Informatics. Brain simulator helps researchers cross the bridge between the cognitive behavior/decease, and the neurophysiology. Brain simulators development is still in infant stage.
Wen-Hsien Tseng, Song-Yun Lu, Hsing Mei
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Epileptogenesis in the developing brain

2013
The neonatal brain has poorly developed GABAergic circuits, and in many of them GABA is excitatory, favoring ictogenicity. Frequently repeated experimental seizures impair brain development in an age-dependent manner. At critical ages, they delay developmental milestones, permanently lower seizure thresholds, and can cause very specific cognitive and ...
Claude G, Wasterlain, David S, Gloss, Jerome, Niquet, Amy S, Wasterlain   +3 more
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Sculpting the Developing Brain

Advances in Pediatrics, 2001
The developing brain experiences major construction during fetal life and for at least the first decade of childhood. Many more neurons and synoptic connections are produced than are needed for later function, and the mature brain is what remains after these excess building materials are "sculpted" away.
M V, Johnston, A, Nishimura, K, Harum, J, Pekar, M E, Blue   +4 more
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Development of the numerical brain

2014
Abstract This article focuses on typical trajectories of numerical cognition from infancy all the way through to adulthood (please note that atypical pathways of numerical cognition will be dealt in‘Brain Correlates of Numerical Disabilities’).
Kaufmann, Liane, Kucian, Karin, von Aster, Michael   +2 more
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Features of the developing brain

Child's Nervous System, 2003
Fetal brain evaluation implies a perfect knowledge of the timing and characteristics of the developing nervous system during gestation.The first half of gestation corresponds to the neurulation, differentiation of primary cerebral vesicles, and neuronogenesis. The second half is characterized by the tremendous growth of the cerebral hemispheres and the
Férechté, Encha-Razavi, Pascale, Sonigo   +1 more
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Experience and Brain Development

Child Development, 1987
This article considers how experience can influence the developing and mature brain and proposes a new categorization scheme based upon the type of information stored and the brain mechanisms that appear to be involved in storing it. In this scheme, experience-expectant information storage refers to incorporation of environmental information that is ...
W T, Greenough, J E, Black, C S, Wallace
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