Results 61 to 70 of about 19,431,511 (358)

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

Molecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang, Anna Schritz, Nikolai Goncharenko, Guy Berchem   +3 more
wiley   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

Strengthening national health research systems in the WHO African Region – progress towards universal health coverage

Globalization and Health, 2019
Background Health challenges and health systems set-ups differ, warranting contextualised healthcare interventions to move towards universal health coverage.
Simbarashe Rusakaniko, Michael Makanga, Martin O. Ota, Moses Bockarie, Geoffrey Banda, Joseph Okeibunor, Francisca Mutapi, Prosper Tumusiime, Thomas Nyirenda, Joses Muthuri Kirigia, Juliet Nabyonga-Orem   +10 more
doaj   +1 more source

Breast cancer screening in developing countries

Clinics, 2017
Developing countries have limited healthcare resources and use different strategies to diagnose breast cancer. Most of the population depends on the public healthcare system, which affects the diagnosis of the tumor.
René Aloísio da Costa Vieira, G. Biller, G. Uemura, C. Ruiz, M. Curado   +4 more
semanticscholar   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Does socioeconomic status of farmers determine the adoption of forest landscape restoration practices? Evidence from Central Togo

Sustainable Environment
Forest Landscape Restoration (FLR) has gained significant attention as a global initiative to address forest and land degradation. While most studies emphasize the diverse benefits of FLR, very few have investigated the extensive nature of its adoption ...
Hamza Moluh Njoya, Kossi Hounkpati, Kossi Adjonou, Kouami Kokou, Stefan Sieber, Katharina Löhr   +5 more
doaj   +1 more source

Just Energy Transition: Learning from the Past for a More Just and Sustainable Hydrogen Transition in West Africa

Land, 2022
The rising demand for energy and the aim of moving away from fossil fuels and to low-carbon power have led many countries to move to alternative sources including solar energy, wind, geothermal energy, biomass, and hydrogen.
Katharina Löhr, Custódio Efraim Matavel, Sophia Tadesse, Masoud Yazdanpanah, Stefan Sieber, Nadejda Komendantova   +5 more
doaj   +1 more source

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

Uveitis in developing countries

Indian Journal of Ophthalmology, 2013
Uveitis, also referred to as intraocular inflammation, is a complex inflammatory process, involving primarily the uveal tract, with or without the involvement of adjacent intraocular structures. The underlying cause of the intraocular inflammation may reside in the uveal tract, retina, lens, or other ocular tissues.
openaire   +4 more sources

Emerging Technologies, STI Diaspora and Science Diplomacy in India: Towards a New Approach

Frontiers in Research Metrics and Analytics, 2022
Utilizing the expertise and knowledge resources of the diaspora, particularly the scientific diaspora, has been part of the strategies of many countries.
Nimita Pandey, Krishna Ravi Srinivas, T. R. Deepthi   +2 more
doaj   +1 more source