Results 251 to 260 of about 638,360 (336)

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

Genome-wide association studies of nutritional traits in peas (Pisum sativum L.) for biofortification. [PDF]

Plant Genome
Ballén-Taborda C, Johnson N, Boatwright L, Lawrence T, Kay J, Windsor N, Madurapperumage A, Thavarajah P, Tang L, Shipe E, Kumar S, Thavarajah D.   +11 more
europepmc   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Nutritional Status and Nitrogen Uptake Dynamics of Waxy-Type Winter Wheat Under Liquid Organic Fertilization. [PDF]

Plants (Basel)
Arlauskienė A, Petraitytė D, Palubinskas T, Jimenez M, Cesevičienė J.   +4 more
europepmc   +1 more source

Autopolyploidization‐Induced Chromatin Remodeling Regulates Leaf Size Variation in Brassica rapa

Advanced Science, EarlyView.
This study demonstrates that monoploid, diploid, and autotetraploid Brassica rapa lines derived from the same genome exhibit distinct leaf morphology. Ploidy changes remodel chromatin accessibility and histone modifications to regulate gene expression, while key transcription factors BrGRF13 and BrARF11 control leaf size and polarity, driving ...
Haoyuan Dong, Yanhong Liu, Yuanming Liu, Shuxin Xuan, Huanhuan Chen, Lai Wei, Guibao Zhang, Hongcui Pei, Zilong Dai, Yanhua Wang, Jinzhu Qiao, Shuangxia Luo, Xueping Chen, Yiguo Hong, Jianjun Zhao, Shuxing Shen, Zefu Lu, Aixia Gu   +17 more
wiley   +1 more source

Pre-harvest bagging modulates fruit traits, phytochemical profiles and disease incidence in mango (Mangifera indica L.) cv. Mallika. [PDF]

Sci Rep
Kumari I, Singh AK, Dimri DC, Singh KP, Nand V, Shivran JS, Gaurav K, Divya, Gangola S, Mitra D, Chattaraj S.   +10 more
europepmc   +1 more source

Proposal for the development of a digital information platform associated with organic crops in sustainable urban agriculture systems.

Muñoz Casas, Camila Andrea, Sánchez Gacharná, Viviana Patricia, Nazarit Marquez, Leimar Denilson   +2 more
openalex   +1 more source

ORGANIC FARMING IS IT A SUSTAINABLE AGRICULTURE ? DEVELOPMENT ISSUES FOR SUSTAINABLE ORGANIC FARMING IN MIDI-PYRENEES REGION

, 2010
Mohamed Gafsi, S. le Tron, C. Mouchet
openalex   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source