Results 1 to 10 of about 77,139 (193)

Follicular development of fetal gonads under the skin of adult mice. [PDF]

Life Med
Abstract Adult ovarian tissues or biopsies isolated from patients prior to chemotherapy or irradiation can reconstitute ovarian functions when transplanted either in the abdomen or subcutaneously. Subcutaneously transplantation avoids invasive surgery and potential risks associated with internal procedures.
Chen J, Liu C, Yu Y, Ye X, Liu L, Zhu Z.
europepmc   +3 more sources

Claude Bernard, the Founder of Modern Medicine

Cells, 2022
Claude Bernard is the first and one of the very few French scientists to have been honored with a national funeral [...]
René Habert
doaj   +1 more source

CEP250 is Required for Maintaining Centrosome Cohesion in the Germline and Fertility in Male Mice

Frontiers in Cell and Developmental Biology, 2022
Male gametogenesis involves both mitotic divisions to amplify germ cell progenitors that gradually differentiate and meiotic divisions. Centrosomal regulation is essential for both types of divisions, with centrioles remaining tightly paired during the ...
Sandrine Floriot, Laura Bellutti, Johan Castille, Pauline Moison, Sébastien Messiaen, Bruno Passet, Laurent Boulanger, Abdelhak Boukadiri, Sophie Tourpin, Christian Beauvallet, Marthe Vilotte, Julie Riviere, Christine Péchoux, Maud Bertaud, Jean-Luc Vilotte, Gabriel Livera   +15 more
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Time-Course Transcriptional and Chromatin Accessibility Profiling Reveals Genes Associated With Asymmetrical Gonadal Development in Chicken Embryos

Frontiers in Cell and Developmental Biology, 2022
In birds, male gonads form on both sides whereas most females develop asymmetric gonads. Multiple early lines of evidence suggested that the right gonad fails to develop into a functional ovary, mainly due to differential expression of PITX2 in the ...
Jianbo Li, Congjiao Sun, Jiangxia Zheng, Junying Li, Guoqiang Yi, Ning Yang   +5 more
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H3K27ac chromatin acetylation and gene expression analysis reveal sex- and situs-related differences in developing chicken gonads

Biology of Sex Differences, 2022
Background Birds exhibit a unique asymmetry in terms of gonad development. The female left gonad generates a functional ovary, whereas the right gonad regresses. In males, both left and right gonads would develop into testes.
Yunqi Jiang, Zhelun Peng, Qiu Man, Sheng Wang, Xiaochen Huang, Lu Meng, Heng Wang, Guiyu Zhu   +7 more
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Seasonal changes of biological condition and reproductive cycle of hampback shrimp Pandalus hypsinotus (Caridea, Pandalidae) in the Tatar Strait

Известия ТИНРО, 2021
Research and commercial trawl catches of humpback shrimp Pandalus hypsinotus from the Tatar Strait (Japan Sea) in 2004–2020 were investigated, with bioanalysis of about 45 thousand specimens. Average timing of group molting, spawning, and eggs laying are
D. N. Yuriev, G. V. Zhukovskaya
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Deletion of Wt1 during early gonadogenesis leads to differences of sex development in male and female adult mice.

PLoS Genetics, 2022
Assessing the role of the WT1 transcription factor (WT1) during early gonad differentiation and its impact on adult sex development has been difficult due to the complete gonadal agenesis and embryonic lethality exhibited by Wt1KO mouse models.
Alejo Torres-Cano, Rosa Portella-Fortuny, Claudia Müller-Sánchez, Sonia Porras-Marfil, Marina Ramiro-Pareta, You-Ying Chau, Manuel Reina, Francesc X Soriano, Ofelia M Martínez-Estrada   +8 more
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RNA-Seq transcriptome data of undifferentiated and differentiated gonads of Siberian sturgeon

Data in Brief, 2020
RNA-Seq transcriptome data from twenty Siberian sturgeon gonads at different developmental stages is described: ten undifferentiated gonads, six gonads of immature males and four gonads from immature females.
Christophe Klopp, André Lasalle, Santiago Di Landro, Denise Vizziano-Cantonnet   +3 more
doaj   +1 more source

Effects of Growth Hormone on Adult Human Gonads: Action on Reproduction and Sexual Function

International Journal of Endocrinology, 2023
Growth hormone (GH), which is commonly considered to be a promoter of growth and development, has direct and indirect effects on adult gonads that influence reproduction and sexual function of humans and nonhumans.
Xin-Yi Zhou, Jia-Ni Ma, Ya-Yin Shen, Xue-Rui Xie, Wei Ren   +4 more
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The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells

Nature Communications, 2020
In meiosis, BRCA2 associates to MEILB2 localising at DNA double-strand breaks (DSBs). Here, the authors identify BRCA2 and MEILB2- associating protein 1 termed BRME1 to work together in regulating meiotic recombination.
Jingjing Zhang, Manickam Gurusaran, Yasuhiro Fujiwara, Kexin Zhang, Meriem Echbarthi, Egor Vorontsov, Rui Guo, Devon F. Pendlebury, Intekhab Alam, Gabriel Livera, Martini Emmanuelle, P. Jeremy Wang, Jayakrishnan Nandakumar, Owen R. Davies, Hiroki Shibuya   +14 more
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