Germ cells in the teleost fish medaka have an inherent feminizing effect. [PDF]
PLoS Genetics, 2018 Germ cells are the only cells that can transfer genetic materials to the next generation via the sperm or egg. However, recent analyses in teleosts revealed another essential role of germ cells: feminizing the gonads.
Toshiya Nishimura +7 more
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Manipulating primordial germ cells from chicken and other bird species [PDF]
The Journal of Reproduction and DevelopmentEmbryonic germ cells are the lineage restricted precursors to the gametes of the adult animal. Embryonic germ cells from birds offer a cellular system for both the conservation and the genetic modification of avian species ...
Marcel H. BLANK +2 more
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Production of live fish derived from frozen germ cells via germ cell transplantation
Stem Cell Research, 2018 The conservation of endangered fish is an urgent issue. Although cryo-banking of fish gametes might ultimately help conserve endangered fish, cryopreservation of fish eggs or embryos is still not possible due to their large size and high yolk content ...
Goro Yoshizaki, Seungki Lee
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Strategies for Mammalian Mesenchymal Stem Cells Differentiation into Primordial Germ Cell-Like Cells: A Review [PDF]
Cell Journal, 2022 Primordial germ cells develop into oocytes and sperm cells. These cells are useful resources in reproductive biology and regenerative medicine. The mesenchymal stem cells (MSCs) have been examined for in vitro production of primordial germ cell-like ...
Shabnam Fayezi +3 more
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SGK1 is essential for meiotic resumption in mammalian oocytes
European Journal of Cell Biology, 2022 In mammalian females, oocytes are stored in the ovary and meiosis is arrested at the diplotene stage of prophase I. When females reach puberty oocytes are selectively recruited in cycles to grow, overcome the meiotic arrest, complete the first meiotic ...
Edgar del Llano +8 more
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Oocyte specific lncRNA variant Rose influences oocyte and embryo development
Non-coding RNA Research, 2021 Fully grown mammalian oocytes store a large amount of RNA synthesized during the transcriptionally active growth stage. A large part of the stored RNA belongs to the long non-coding class which contain either transcriptional noise or important ...
Rajan Iyyappan +5 more
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Metabolic pathways regulating the development and non-genomic heritable traits of germ cells
The Journal of Reproduction and Development, 2021 Metabolism is an important cellular process necessary not only for producing energy and building blocks for cells, but also for regulating various cell functions, including intracellular signaling, epigenomic effects, and transcription.
Yasuhisa MATSUI, Yohei HAYASHI
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Cyp26b1 expression in murine Sertoli cells is required to maintain male germ cells in an undifferentiated state during embryogenesis. [PDF]
PLoS ONE, 2009 In mammals, germ cells within the developing gonad follow a sexually dimorphic pathway. Germ cells in the murine ovary enter meiotic prophase during embryogenesis, whereas germ cells in the embryonic testis arrest in G0 of mitotic cell cycle and do not ...
Hui Li +4 more
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In vitro germ cell differentiation from cynomolgus monkey embryonic stem cells. [PDF]
PLoS ONE, 2009 BACKGROUND: Mouse embryonic stem (ES) cells can differentiate into female and male germ cells in vitro. Primate ES cells can also differentiate into immature germ cells in vitro.
Kaori Yamauchi +4 more
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Frontiers in Cell and Developmental Biology, 2020 Formation of the hatching mouse blastocyst marks the end of preimplantation development, whereby previous cell cleavages culminate in the formation of three distinct cell lineages (trophectoderm, primitive endoderm and epiblast).
Giorgio Virnicchi +5 more
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