Tre1, a G protein-coupled receptor, directs transepithelial migration of Drosophila germ cells.
PLoS Biology, 2003 In most organisms, germ cells are formed distant from the somatic part of the gonad and thus have to migrate along and through a variety of tissues to reach the gonad.
Prabhat S Kunwar +4 more
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Germinal Epithelium Cytology during Spermatogenesis in the Alligator Snapping Turtle, Macrochelys temminckii (Reptilia: Chelydridae) [PDF]
, 2018 We investigated the cytology of the seminiferous epithelia of the Alligator Snapping Turtle (Macrochelys temminckii). Spermatogenic and regressed testes were assessed from 2 adult individuals collected in Arkansas in May and September of 1993 ...
Gribbins, Kevin M., Trauth, Stanley E.
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WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary. [PDF]
PLoS ONE, 2010 Female germ cells are essential for organogenesis of the ovary; without them, ovarian follicles do not form and functional and structural characteristics of the ovary are lost.
Chia-Feng Liu +2 more
doaj +1 more source
CPEB3 Maintains Developmental Competence of the Oocyte
CellsMammalian oocyte development depends on the temporally controlled translation of maternal transcripts, particularly in the coordination of meiotic and early embryonic development when transcription has ceased.
Lucie Lamacova +9 more
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Primary Culture System for Germ Cells from Caenorhabditis elegans Tumorous Germline Mutants
Bio-Protocol, 2017 The Caenorhabditis elegans germ line is an important model system for the study of germ stem cells. Wild-type C. elegans germ cells are syncytial and therefore cannot be isolated in in vitro cultures. In contrast, the germ cells from tumorous mutants can
Alexandra Vagasi +3 more
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Cell cycle regulation for meiosis in mammalian germ cells
The Journal of Reproduction and Development, 2023 In mouse fetal gonads, germ cell development is accompanied by changes in cell cycle mode in response to external signals and intrinsic mechanisms of cells.
Ryuki SHIMADA, Kei-ichiro ISHIGURO
doaj +1 more source
PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation. [PDF]
, 2018 Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate.
Chen, Di +4 more
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PLoS ONE, 2011 Differentiation of germ cells into male gonocytes or female oocytes is a central event in sexual reproduction. Proliferation and differentiation of fetal germ cells depend on the sex of the embryo.
Anne-Amandine Chassot +6 more
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Over Expression of NANOS3 and DAZL in Human Embryonic Stem Cells. [PDF]
PLoS ONE, 2016 The mechanisms underlying human germ cell development are largely unknown, partly due to the scarcity of primordial germ cells and the inaccessibility of the human germline to genetic analysis.
Sarita Panula +12 more
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An Extended Culture System that Supports Human Primordial Germ Cell-like Cell Survival and Initiation of DNA Methylation Erasure. [PDF]
, 2020 The development of an in vitro system in which human primordial germ cell-like cells (hPGCLCs) are generated from human pluripotent stem cells (hPSCs) has been invaluable to further our understanding of human primordial germ cell (hPGC) specification ...
Bower, Grace +9 more
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