Results 1 to 10 of about 18,030 (201)

Zebrafish Primordial Germ Cell Migration [PDF]

Frontiers in Cell and Developmental Biology, 2021
Similar to many other organisms, zebrafish primordial germ cells (PGCs) are specified at a location distinct from that of gonadal somatic cells. Guided by chemotactic cues, PGCs migrate through embryonic tissues toward the region where the gonad develops.
Anne Aalto, Adan Olguin-Olguin, Erez Raz
doaj   +3 more sources

Chicken Primordial Germ Cell Surface Marker [PDF]

Animals
The creation of transgenic chickens holds significant promise for the agricultural and biotechnological sectors, offering potential improvements in disease resistance and production efficiency.
Tamara J. Gough, Terry G. Wise, Matthew P. Bruce, Timothy J. Doran, Daniel S. Layton, Andrew G. D. Bean   +5 more
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Germ cell dynamics during nest breakdown and formation of the primordial follicle pool in the domestic turkey (Meleagris gallopavo)

Poultry Science, 2020
This study determined, for the first time, the different subpopulations of germ cells and stereological changes within the cortex of the functional left ovary during germ cell nest breakdown, and formation of the primordial follicle pool in the domestic ...
G.B. Hall, J.A. Long, B.J. Wood, G.Y. Bedecarrats   +3 more
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An Extended Culture System that Supports Human Primordial Germ Cell-like Cell Survival and Initiation of DNA Methylation Erasure

Stem Cell Reports, 2020
Summary: The development of an in vitro system in which human primordial germ cell-like cells (hPGCLCs) are generated from human pluripotent stem cells (hPSCs) has been invaluable to further our understanding of human primordial germ cell (hPGC ...
Joanna J. Gell, Wanlu Liu, Enrique Sosa, Alex Chialastri, Grace Hancock, Yu Tao, Sissy E. Wamaitha, Grace Bower, Siddharth S. Dey, Amander T. Clark   +9 more
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Strategies for Mammalian Mesenchymal Stem Cells Differentiation into Primordial Germ Cell-Like Cells: A Review [PDF]

Cell Journal, 2022
Primordial germ cells develop into oocytes and sperm cells. These cells are useful resources in reproductive biology and regenerative medicine. The mesenchymal stem cells (MSCs) have been examined for in vitro production of primordial germ cell-like ...
Shabnam Fayezi, Parisa Fayyazpour, Zahra Norouzi, Amir Mehdizadeh   +3 more
doaj   +1 more source

Exploration of GES-induced masculinization of Gambusia affinis Based on Single Cell Level

Guangdong nongye kexue, 2023
【Objective】To investigate the molecular mechanism of sex reversal in female Western mosquitofish (Gambusia affinis) under the effect of gestodene (GES) by studying the development of gonadal cell differentiation and gene expression changes involved in ...
Tingyin FENG, Xikai DENG, Ke XING
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Transcription factor TFAP2C regulates major programs required for murine fetal germ cell maintenance and haploinsufficiency predisposes to teratomas in male mice. [PDF]

PLoS ONE, 2013
Maintenance and maturation of primordial germ cells is controlled by complex genetic and epigenetic cascades, and disturbances in this network lead to either infertility or malignant aberration.
Jana Schemmer, Marcos J Araúzo-Bravo, Natalie Haas, Sabine Schäfer, Susanne N Weber, Astrid Becker, Dawid Eckert, Andreas Zimmer, Daniel Nettersheim, Hubert Schorle   +9 more
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Efficient generation of marmoset primordial germ cell-like cells using induced pluripotent stem cells

eLife, 2023
Reconstitution of germ cell fate from pluripotent stem cells provides an opportunity to understand the molecular underpinnings of germ cell development.
Yasunari Seita, Keren Cheng, John R McCarrey, Nomesh Yadu, Ian H Cheeseman, Alec Bagwell, Corinna N Ross, Isamar Santana Toro, Li-hua Yen, Sean Vargas, Christopher S Navara, Brian P Hermann, Kotaro Sasaki   +12 more
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Generation of NANOS3-mCherry reporter human embryonic stem cell line SYSUe-009-A using CRISPR/Cas9

Stem Cell Research, 2023
NANOS3 is a zinc-finger containing RNA-binding protein that has been demonstrated to be highly expressed in human primordial germ cell(hPGC), thus NANOS3 can serve as a marker for hPGC development.
Ruirui Guo, Simin Yuan, Bing Li, Jichang Wang, Chuanbo Sun   +4 more
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Sex Specification and Heterogeneity of Primordial Germ Cells in Mice.

PLoS ONE, 2015
In mice, primordial germ cells migrate into the genital ridges by embryonic day 13.5 (E13.5), where they are then subjected to a sex-specific fate with female and male primordial germ cells undergoing mitotic arrest and meiosis, respectively.
Akihiko Sakashita, Yukiko Kawabata, Yuko Jincho, Shiun Tajima, Soichiro Kumamoto, Hisato Kobayashi, Yasuhisa Matsui, Tomohiro Kono   +7 more
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