Results 11 to 20 of about 18,030 (201)
Primordial Germ Cell Specification and Migration [version 1; referees: 3 approved] [PDF]
F1000Research, 2015 Primordial germ cells are the progenitor cells that give rise to the gametes. In some animals, the germline is induced by zygotic transcription factors, whereas in others, primordial germ cell specification occurs via inheritance of maternally provided ...
Florence Marlow
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Primordial Germ Cells in Mice [PDF]
Cold Spring Harbor Perspectives in Biology, 2012 Germ cell development creates totipotency through genetic as well as epigenetic regulation of the genome function. Primordial germ cells (PGCs) are the first germ cell population established during development and are immediate precursors for both the oocytes and spermatogonia.
Mitinori, Saitou, Masashi, Yamaji
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Mammalian primordial germ cell specification [PDF]
Development, 2021 ABSTRACT The peri-implantation window of mammalian development is the crucial window for primordial germ cell (PGC) specification. Whereas pre-implantation dynamics are relatively conserved between species, the implantation window marks a stage of developmental divergence between key model organisms, and thus potential variance in the ...
Grace V. Hancock +3 more
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PAR6, a potential marker for the germ cells selected to form primordial follicles in mouse ovary. [PDF]
PLoS ONE, 2009 Partitioning-defective proteins (PAR) are detected to express mainly in the cytoplast, and play an important role in cell polarity. However, we showed here that PAR6, one kind of PAR protein, was localized in the nuclei of mouse oocytes that formed ...
Jing Wen +10 more
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Functional analysis of the Drosophila embryonic germ cell transcriptome by RNA interference. [PDF]
PLoS ONE, 2014 In Drosophila melanogaster, primordial germ cells are specified at the posterior pole of the very early embryo. This process is regulated by the posterior localized germ plasm that contains a large number of RNAs of maternal origin.
Ferenc Jankovics +6 more
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Analysis of chicken primordial germ cells [PDF]
Cytotechnology, 2008 Primordial germ cells (PGCs) are precursors of germline cells. Although avian PGCs have been used to produce transgenic birds, their characteristics largely remain unknown. In this study, we isolated PGCs from chicken embryos at various developmental stages and analyzed the gene expression.
Makoto, Motono +3 more
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Collectively stabilizing and orienting posterior migratory forces disperses cell clusters in vivo
Nature Communications, 2020 During development, primordial germ cell clusters undergo dispersal but how cell–cell adhesion and contractility are coordinated during this process in vivo is unclear. Here, the authors show that Drosophila primordial germ cells utilize migratory forces
B. Lin, J. Luo, R. Lehmann
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Stem Cell Research, 2017 Primordial germ cells undergo three significant processes on their path to becoming primary oocytes: the initiation of meiosis, the formation and breakdown of germ cell nests, and the assembly of single oocytes into primordial follicles.
Roseanne Rosario +2 more
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Follistatin288 Regulates Germ Cell Cyst Breakdown and Primordial Follicle Assembly in the Mouse Ovary. [PDF]
PLoS ONE, 2015 In mammals, the primordial follicle pool represents the entire reproductive potential of a female. The transforming growth factor-β (TGF-β) family member activin (ACT) contributes to folliculogenesis, although the exact mechanism is not known.
Zhengpin Wang +6 more
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Nature, 1980 Primordial Germ Cells in the Chordates. By P.D. Nieuwkoop and L.A. Sutasurya. Pp.187. (Cambridge University Press: Cambridge, 1979.) £14.50.
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