Results 1 to 10 of about 100,022 (216)

The Function of Cumulus Cells in Oocyte Growth and Maturation and in Subsequent Ovulation and Fertilization

Cells, 2021
Cumulus cells (CCs) originating from undifferentiated granulosa cells (GCs) differentiate in mural granulosa cells (MGCs) and CCs during antrum formation in the follicle by the distribution of location. CCs are supporting cells of the oocyte that protect
Bongkoch Turathum, Ri-Cheng Chian
exaly   +3 more sources

The Role of Oocyte Organelles in Determining Developmental Competence

Biology, 2017
The ability of an oocyte to undergo successful cytoplasmic and nuclear maturation, fertilization and embryo development is referred to as the oocyte’s quality or developmental competence.
Jo-Ann Stanton, Jennifer Juengel, Karen Reader   +2 more
exaly   +3 more sources

Isolation and in vitro Culture of Mouse Oocytes

Bio-Protocol, 2021
Females are endowed at birth with a fixed reserve of oocytes, which declines both in quantity and quality with advancing age. Understanding the molecular mechanisms regulating oocyte quality is crucial for improving the chances of pregnancy success in ...
Jessica Greaney, Goutham Narayanan Subramanian, Yunan Ye, Hayden Homer   +3 more
doaj   +1 more source

The oocyte spindle midzone pauses Cdk1 inactivation during fertilization to enable male pronuclear formation and embryo development

Cell Reports, 2022
Summary: Inactivation of cyclin-dependent kinase 1 (Cdk1), controlled by cyclin B1 proteolysis, orders events during mitotic exit. Here, we used a FRET biosensor to study Cdk1 activity while simultaneously monitoring anaphase II and pronuclear (PN ...
Chenxi Zhou, Hayden A. Homer
doaj   +1 more source

Lipid Metabolism Was Associated With Oocyte in vitro Maturation in Women With Polycystic Ovarian Syndrome Undergoing Unstimulated Natural Cycle

Frontiers in Cell and Developmental Biology, 2021
ObjectiveHyperlipidemia are common polycystic ovarian syndrome (PCOS)-related metabolic dysfunctions and can adversely affect assisted reproductive technology (ART) outcomes in controlled ovarian hyperstimulation (COH) cycles. The objective of this study
Tao Liu, Tao Liu, Tao Liu, Tao Liu, Tao Liu, Dongming Liu, Dongming Liu, Dongming Liu, Dongming Liu, Dongming Liu, Xueling Song, Xueling Song, Xueling Song, Xueling Song, Xueling Song, Jiangxue Qu, Jiangxue Qu, Jiangxue Qu, Jiangxue Qu, Jiangxue Qu, Xiaoying Zheng, Xiaoying Zheng, Xiaoying Zheng, Xiaoying Zheng, Xiaoying Zheng, Jia Li, Jia Li, Jia Li, Jia Li, Jia Li, Rui Yang, Rui Yang, Rui Yang, Rui Yang, Rui Yang, Shuo Yang, Shuo Yang, Shuo Yang, Shuo Yang, Shuo Yang, Xi Zhang, Xi Zhang, Xi Zhang, Xi Zhang, Xi Zhang, Haiyan Wang, Haiyan Wang, Haiyan Wang, Haiyan Wang, Haiyan Wang, Liying Yan, Liying Yan, Liying Yan, Liying Yan, Liying Yan, Caihong Ma, Caihong Ma, Caihong Ma, Caihong Ma, Caihong Ma, Rong Li, Rong Li, Rong Li, Rong Li, Rong Li, Jie Yan, Jie Yan, Jie Yan, Jie Yan, Jie Yan, Jie Qiao, Jie Qiao, Jie Qiao, Jie Qiao, Jie Qiao   +74 more
doaj   +1 more source

A PP2A-B56—Centered View on Metaphase-to-Anaphase Transition in Mouse Oocyte Meiosis I

Cells, 2020
Meiosis is required to reduce to haploid the diploid genome content of a cell, generating gametes—oocytes and sperm—with the correct number of chromosomes.
Leonor Keating, Sandra A. Touati, Katja Wassmann   +2 more
doaj   +1 more source

The Presence of Immature GV− Stage Oocytes during IVF/ICSI Is a Marker of Poor Oocyte Quality: A Pilot Study

Medical Sciences, 2020
Here we investigate whether the presence of germinal vesicle-stage oocytes (GV− oocytes) reflects poor oocyte developmental competence (or quality).
Pia Astbury, Goutham N. Subramanian, Jessica Greaney, Chris Roling, Jacqui Irving, Hayden A. Homer   +5 more
doaj   +1 more source

Filopodia-like protrusions of adjacent somatic cells shape the developmental potential of oocytes

Life Science Alliance, 2023
Filopodia-like protrusions sent by the somatic cells to the oocyte play a role in the structural integrity of the germline–somatic complex, and regulate gene expression in the oocyte and thus its developmental potential and chances to produce a viable ...
Flora Crozet, Gaëlle Letort, Rose Bulteau, Christelle Da Silva, Adrien Eichmuller, Anna Francesca Tortorelli, Joséphine Blévinal, Morgane Belle, Julien Dumont, Tristan Piolot, Aurélien Dauphin, Fanny Coulpier, Alain Chédotal, Jean-Léon Maître, Marie-Hélène Verlhac, Hugh J Clarke, Marie-Emilie Terret   +16 more
doaj   +1 more source

An Eight Year Experience of Autologous Oocyte Vitrification for Infertile Patients Owing to Unavailability of Sperm on Oocyte Retrieval Day

Frontiers in Medicine, 2021
Objective: The objective of this study was to provide a descriptive analysis of the clinical outcomes achieved in oocyte vitrification in cases where sperm was unavailable on oocyte retrieval day, and to identify predictors of oocyte survival.Methods ...
Xiao Fu, Xiao Fu, Xiao Fu, Xiaojie Liu, Xiaojie Liu, Xiaojie Liu, Jing Li, Jing Li, Jing Li, Meng Zhang, Meng Zhang, Meng Zhang, Jingjing Jiang, Jingjing Jiang, Qianqian Chen, Qianqian Chen, Mei Li, Mei Li, Shanshan Gao, Shanshan Gao, Shanshan Gao, Jinlong Ma, Jinlong Ma   +22 more
doaj   +1 more source

Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry

Nature Communications, 2020
Meiotic cell division in oocytes is asymmetric and requires microtubule spindle migration after anaphase-onset. Here, the authors show that Nampt, an enzyme of the Nicotinamide adenine dinucleotide (NAD) biosynthetic pathway, contributes to post-anaphase
Zhe Wei, Jessica Greaney, Wei-Guo Nicholas Loh, Hayden Anthony Homer   +3 more
doaj   +1 more source