Results 41 to 50 of about 132,905 (308)

The Xenopus Oocyte System: Molecular Dynamics of Maturation, Fertilization, and Post-Ovulatory Fate

Biomolecules
The Xenopus oocyte has long served as a versatile and powerful model for dissecting the molecular underpinnings of reproductive and developmental processes. Its large size, manipulability, and well-characterized cell cycle states have enabled generations
Ken-Ichi Sato
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

The generation of live offspring from vitrified oocytes [PDF]

, 2011
Oocyte cryopreservation is extremely beneficial for assisted reproductive technologies, the treatment of infertility and biotechnology and offers a viable alternative to embryo freezing and ovarian grafting approaches for the generation of embryonic stem
Sanchez-Partida, Luis, Sumer, Huseyin, Sumer, H, Kelly, Richard, Lo, Camden, Kelly, RDW, Aharon, R, Moira K. O'Bryan, Kelly Richard D. W., Michael K. Holland, Camden Y. Lo, O'Bryan Moira K., St. John, Justin C., Justin C St John, Camden Y Lo, St John, Justin C., L. Gabriel Sanchez-Partida, Sumner, Huseyin, Sanchez-Partida L. Gabriel, John St., JC, St John, Justin, Sanchez-Partida, L. Gabriel, Richard D W Kelly, Michael K Holland, Moira K O'Bryan, St. John Justin C., Aharon Rotem, Sumer Huseyin, Lo Camden Y., Holland, Michael K., O'Bryan, Moira K., Rotem Aharon, Aharon, Rotem, Justin C. St. John, Holland Michael K., Sanchez-Partida, LG, O'Bryan, Moira, Lo, CY, Holland, MK, Lo, Camden Y., Huseyin Sumer, L Gabriel Sanchez-Partida, Richard D. W. Kelly, Kelly, Richard D. W., Sanchez-Partilda, L. Gabriel, O'Bryan, MK, Holland, Michael   +46 more
core   +1 more source

Functional Roles of Src Kinase Activity in Oocyte Maturation and Artificial Egg Activation in Xenopus laevis

Cells
Src family tyrosine kinases regulate oocyte maturation and fertilization in many species, yet their physiological roles in Xenopus laevis (X. laevis) remain incompletely defined. Here, we generated three X. laevis Src (xSrc) constructs with defined point
Ken-ichi Sato, Alexander A. Tokmakov
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Regulation of the maternal-to-embryonic transition in "C. elegans" [PDF]

, 2012
Reproduction is a fundamental process of life which allows the survival of each species through the birth of young species members. Several modes of reproduction evolved and are classified into sexual and asexual reproduction.
Finger, Susanne
core   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Oocyte-expression-Cas9 strategy efficiently attenuates the allele complexity in F0 mice.

, 2016
Oocyte-expression-Cas9 strategy efficiently attenuates the allele complexity in F0 mice.
Jiankui Zhou (225023), Ningning Hou (2633680), Xingxu Huang (39402), Yun Shi (172065), Xin Lou (487486), Linlin Zhang (131810), Bian Hu (225019), Jinxiong Han (2633677)   +7 more
core   +1 more source

Assisted Oocyte Activation Method (Ca ACTIVATION) Improves Fertilization in Patients with Recurrent Fertilization Failure

, 2022
: Total fertilization failure (TFF) happens in 1–3% of total intracytoplasmic sperm injection (ICSI) cycles and may reoccur in sequent cycles. Regardless the high success rate with the applying of intracytoplasmic sperm injection (ICSI), there's still a ...
Mohammed H. Sayed Ahmad, Bahgat A. El-Fiky, Ayman S. El-Dorghamy   +2 more
core   +1 more source

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi, David J. Sharkey, Nicole O. McPherson, Markos Negash Alemie, Krasimir Vasilev, Sarah A. Robertson   +5 more
wiley   +1 more source