Results 41 to 50 of about 100,022 (216)
Advanced Science, EarlyView.Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang +6 more
wiley +1 more source
Advanced Science, EarlyView.Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae +5 more
wiley +1 more source
Oocyte In Vitro Maturation with Crude Sperm Extract Protein of Bull's Spermatozoa
Journal of Experimental Life Science, 2016 Oocyte In vitro maturation (IVM) is one of the important parts for in vitro fertilization (IVF). The success of oocyte maturation is influenced by the composit ion and the quality of IVM medium.
Bilqis Bilqis, Sri Rahayu, Gatot Ciptadi
doaj +1 more source
Advanced Science, EarlyView.This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu +23 more
wiley +1 more source
From Cytoskeletal Remodeling to Oocyte Quality: The Emerging Role of Mechanics
Advanced ScienceOocyte quality is essential for successful fertilization and embryonic development. At the end of mammalian oogenesis, oocytes undergo two highly asymmetric meiotic divisions that preserve maternal reserves while generating a haploid gamete.
Anastasia Shihabi +3 more
doaj +1 more source
The Effect of the Follicle Size and Follicle Number Per Ovary on Oocyte Quality of Local Goat
Jurnal Kedokteran Hewan, 2007 This research was aimed to find out the relationship between the diameter of follicle and the different of follicle number on oocyte quality of local goat. The oocyte originated from the ovary was taken from the Slaughterhouse in Banda Aceh.
Arman Sayuti +4 more
doaj +1 more source
Advanced Science, EarlyView.The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng +8 more
wiley +1 more source
Advanced Science, EarlyView.Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao +15 more
wiley +1 more source
Advanced Science, EarlyView.A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu +27 more
wiley +1 more source
Reproductive Biology and Endocrinology, 2009 Background Ovarian stimulation for assisted reproductive technology (ART) overcomes the physiologic process to develop a single dominant follicle. However, following stimulation, egg recovery rates are not 100%.
Rinaudo Paolo F +7 more
doaj +1 more source