Results 1 to 10 of about 87,639 (309)

Follicular fluid content and oocyte quality: from single biochemical markers to metabolomics [PDF]

Reproductive Biology and Endocrinology, 2009
The assessment of oocyte quality in human in vitro fertilization (IVF) is getting increasing attention from embryologists. Oocyte selection and the identification of the best oocytes, in fact, would help to limit embryo overproduction and to improve the ...
Massobrio Marco, Molinari Emanuela, Casano Simona, Piane Luisa, Revelli Alberto, Rinaudo Paolo   +5 more
doaj   +4 more sources

Abnormal cholesterol–cholesteryl ester metabolism impairs mouse oocyte quality during ovarian aging [PDF]

Cellular & Molecular Biology Letters
Background Ovarian aging-induced decline in oocyte quality has been a main issue in women of advanced maternal age. However, the potential mechanism remains elusive, and there are no effective strategies to ameliorate aged oocyte quality.
Sainan Zhang, Bichun Guo, Junshun Fang, Shanshan Wang, Yicen Liu, Die Wu, Nannan Kang, Yang Zhang, Xin Zhen, Guijun Yan, Lijun Ding, Haixiang Sun, Chuanming Liu   +12 more
doaj   +2 more sources

Comprehensive mathematical modeling of age-dependent oocyte quality and quantity for predicting live birth rate [PDF]

Frontiers in Endocrinology
BackgroundAge-related decline in fertility is widely recognized. However, a quantitative evaluation of changes in oocyte quality and quantity remains insufficient.
Toshio Sujino, Tatsuyuki Ogawa, Akira Komiya, Akira Komiya, Makiko Tajima, Yuko Takayanagi, Yurie Nako, Hayata Nakajo, Kenichiro Hiraoka, Isao Tamura, Hidetoshi Yamashita, Kiyotaka Kawai   +11 more
doaj   +2 more sources

Diffused Intra-Oocyte Hydrogen Peroxide Activates Myeloperoxidase and Deteriorates Oocyte Quality. [PDF]

PLoS ONE, 2015
Hydrogen peroxide (H2O2) is a relatively long-lived signaling molecule that plays an essential role in oocyte maturation, implantation, as well as early embryonic development. Exposure to relatively high levels of H2O2 functions efficiently to accelerate
Sana N Khan, Faten Shaeib, Tohid Najafi, Mahendra Kavdia, Bernard Gonik, Ghassan M Saed, Pravin T Goud, Husam M Abu-Soud   +7 more
doaj   +4 more sources

Vitamins, Coenzyme Q10, and Antioxidant Strategies to Improve Oocyte Quality in Women with Gynecological Cancers: A Comprehensive Review [PDF]

Antioxidants
Background: Gynecological cancers, including ovarian, cervical, and endometrial cancers, significantly affect both survival and reproductive health in women.
Isaic Alexandru, Daciana Nistor, Alexandru Catalin Motofelea, Bianca-Astrid Cadar (Andone), Andreea Crintea, Carmen Tatu, Gheorghe Nicusor Pop, Andrei Nicolae Csep   +7 more
doaj   +2 more sources

Maternal obesity and oocyte quality

生物医学转化, 2022
With an escalating global epidemic of obesity, the prevalence of obesity among reproductive women continues to rise. It has been widely reported that maternal obesity has profound effects on female reproduction.
Tang Shoubin, Han Longsen, Wang Qiang
doaj   +2 more sources

BDNF secreted by mesenchymal stem cells improves aged oocyte quality and development potential by activating the ERK1/2 pathway [PDF]

Cell Communication and Signaling
Background Reduced oocyte quality is a key factor in age-related fertility decline, and there are no effective treatments available. The secretome of mesenchymal stem cells (MSC-sec) contains various bioactive factors and has the potential to improve ...
Jing Zhou, Cheng Li, Xin Mi, Jiali Zhou, Caiyi Chen, Jiayi Ren, Ran Liu, Gang Liu, Zi-Jiang Chen, Yingying Qin, Keliang Wu, Shidou Zhao   +11 more
doaj   +2 more sources

Oocyte quality and aging

JBRA Assisted Reproduction, 2021
It is well known that female reproduction ability decreases during the forth decade of life due to age-related changes in oocyte quality and quantity; although the number of women trying to conceive has today increased remarkably between the ages of 36 to 44.
Moghadam, Ali Reza Eftekhari, Moghadam, Mahin Taheri, Hemadi, Masoud, Saki, Ghasem   +3 more
openaire   +3 more sources

Endometriosis, Oocyte, and Embryo Quality

Journal of Clinical Medicine, 2023
Endometriosis is a common finding among women with infertility, and women who are diagnosed with endometriosis are almost twice as likely to experience infertility. Mechanisms by which endometriosis causes infertility remain poorly understood. In this review, we evaluate the current literature on the impact of endometriosis on oocyte and embryo quality.
Sania Latif, Ertan Saridogan
openaire   +2 more sources

Role of Lipid Metabolism and Signaling in Mammalian Oocyte Maturation, Quality, and Acquisition of Competence

Frontiers in Cell and Developmental Biology, 2021
It has been found that the quality of oocytes from obese women has been compromised and subsequent embryos displayed arrested development. The compromised quality may be either due to the poor or rich metabolic conditions such as imbalance or excession ...
Ranjha Khan, Xiaohua Jiang, Uzma Hameed, Qinghua Shi   +3 more
doaj   +1 more source