Results 11 to 20 of about 87,639 (309)

Human oocyte quality and reproductive health

Science Bulletin
Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and key processes affecting oocyte quality involve the secretion of and response to hormones, ovarian function, oogenesis, oocyte maturation, and meiosis.
Zhihua, Zhang, Tianyu, Wu, Qing, Sang, Lei, Wang   +3 more
openaire   +4 more sources

Improvement of oocyte quality through the SIRT signaling pathway

Reproductive Medicine and Biology, 2023
Background Oocyte quality is one of the major deciding factors in female fertility competence. Methods PubMed database was searched for reviews by using the following keyword “oocyte quality” AND “Sirtuins”.
Kim Cat Tuyen Vo, Yorino Sato, Kazuhiro Kawamura   +2 more
doaj   +1 more source

Reorganization, specialization, and degradation of oocyte maternal components for early development

Reproductive Medicine and Biology, 2023
Background Oocyte components are maternally provided, solely determine oocyte quality, and coordinately determine embryo quality with zygotic gene expression.
Yuhkoh Satouh, Ken Sato
doaj   +1 more source

Non-invasive oocyte quality assessment

Biology of Reproduction, 2022
Abstract Oocyte quality is perhaps the most important limiting factor in female fertility; however, the current methods of determining oocyte competence are only marginally capable of predicting a successful pregnancy. We aim to review the predictive value of non-invasive techniques for the assessment of human oocytes and their related ...
Romualdo, Sciorio, Daniel, Miranian, Gary D, Smith   +2 more
openaire   +2 more sources

Maternal diabetes and oocyte quality [PDF]

Mitochondrion, 2010
Maternal diabetes has been demonstrated to adversely affect preimplantation embryo development and pregnancy outcomes. Emerging evidence has implicated that these effects are associated with compromised oocyte competence. Several developmental defects during oocyte maturation in diabetic mice have been reported over past decades.
Qiang, Wang, Kelle H, Moley
openaire   +2 more sources

Gut microbiota–bile acid‐vitamin D axis plays an important role in determining oocyte quality and embryonic development

Clinical and Translational Medicine, 2023
Objective To reveal whether gut microbiota and their metabolites are correlated with oocyte quality decline caused by circadian rhythm disruption, and to search possible approaches for improving oocyte quality.
Ang Li, Fei Li, Wei Song, Zi‐Li Lei, Qian‐Qian Sha, Shao‐Yuan Liu, Chang‐Yin Zhou, Xue Zhang, Xiao‐Zhen Li, Heide Schatten, Teng Zhang, Qing‐Yuan Sun, Xiang‐Hong Ou   +12 more
doaj   +1 more source

The role of mitophagy during oocyte aging in human, mouse, and Drosophila: implications for oocyte quality and mitochondrial disease

Reproduction and Fertility, 2021
There is a worldwide trend for women to have their first pregnancy later in life. However, as oocyte quality declines with maternal aging, this trend leads to an increase in subfertility.
Rachel T Cox, Joanna Poulton, Suzannah A Williams   +2 more
doaj   +1 more source

NAD+ Repletion Rescues Female Fertility during Reproductive Aging

Cell Reports, 2020
Summary: Reproductive aging in female mammals is an irreversible process associated with declining oocyte quality, which is the rate-limiting factor to fertility. Here, we show that this loss of oocyte quality with age accompanies declining levels of the
Michael J. Bertoldo, Dave R. Listijono, Wing-Hong Jonathan Ho, Angelique H. Riepsamen, Dale M. Goss, Dulama Richani, Xing L. Jin, Saabah Mahbub, Jared M. Campbell, Abbas Habibalahi, Wei-Guo Nicholas Loh, Neil A. Youngson, Jayanthi Maniam, Ashley S.A. Wong, Kaisa Selesniemi, Sonia Bustamante, Catherine Li, Yiqing Zhao, Maria B. Marinova, Lynn-Jee Kim, Laurin Lau, Rachael M. Wu, A. Stefanie Mikolaizak, Toshiyuki Araki, David G. Le Couteur, Nigel Turner, Margaret J. Morris, Kirsty A. Walters, Ewa Goldys, Christopher O’Neill, Robert B. Gilchrist, David A. Sinclair, Hayden A. Homer, Lindsay E. Wu   +33 more
doaj   +1 more source

Methylglyoxal-dependent glycative stress and deregulation of SIRT1 functional network in the ovary of PCOS mice [PDF]

, 2020
Advanced glycation end-products (AGEs) are involved in the pathogenesis and consequences of polycystic ovary syndrome (PCOS), a complex metabolic disorder associated with female infertility.
Amicarelli, F, Cristiano, L, D'Alessandro, AM, Emidio, GD, Falone, S, Nottola, S, Palmerini, MG, Placidi, M, Rea, F, Rossi, G, Tatone, C   +10 more
core   +1 more source

The Role of Oocyte Organelles in Determining Developmental Competence

Biology, 2017
The ability of an oocyte to undergo successful cytoplasmic and nuclear maturation, fertilization and embryo development is referred to as the oocyte’s quality or developmental competence.
Karen L. Reader, Jo-Ann L. Stanton, Jennifer L. Juengel   +2 more
doaj   +1 more source