Results 21 to 30 of about 248,167 (261)

Stem cells in the ovary [PDF]

, 2009
For decades, scientists have thought that female mammals are born with a lifetime supply of oocytes in the ovary, irreversibly destined to decline after birth.
Tomaszczuk-Kossowska, Katarzyna
core   +1 more source

Expression of activin subunits and receptors in the developing human ovary:activin A promotes germ cell survival and proliferation before primordial follicle formation [PDF]

, 2004
The formation of the essential functional unit of the ovary, the primordial follicle, occurs during fetal life in humans. Factors regulating oogonial proliferation and interaction with somatic cells before primordial follicle formation are largely ...
Bayne, R A L, Cambray, N, Martins da Silva, S J, Hartley, P S, McNeilly, A S, Martins da Silva, S J; id_orcid, Anderson, R A   +6 more
core   +1 more source

Germ cell chromatin

Biology of Reproduction
Abstract During mammalian gametogenesis, the chromatin landscape is especially dynamic. Primordial germ cells (PGCs), the precursors to mature male and female gametes, are a transient and small cell population that undergoes profound epigenetic reprogramming. Our knowledge of this process has come primarily from descriptive studies of
Stylianos Bakoulis, Kathleen R Stewart-Morgan   +1 more
openaire   +3 more sources

The genome and the germ cell.

Genome biology, 2003
A report on the third biennial Cold Spring Harbor Laboratory meeting on Germ Cells, Cold Spring Harbor, USA, 9-13 October 2002.
Molyneaux, Kathleen, Wylie, Christopher
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Slow Turning Lateral Vessel Bioreactor Improves Embryoid Body Formation and Cardiogenic Differentiation of Mouse Embryonic Stem Cells.

, 2013
Embryonic stem cells (ESCs) have the ability to form aggregates, which are called embryoid bodies (EBs). EBs mimic early embryonic development and are commonly produced for cardiomyogenesis.
Tharasanit, T., Biology of Reproductive Cells, Pirity, M., Rungarunlert, Sasitorn, Klincumhom, Nuttha, Rungarunlert, S., Dinnyés, András, Tharasanit, Theerawat, Dep Gezondheidszorg Landbouwhuisdieren, Klincumhom, N., Techakumphu, M., Pirity, Melinda, Dinnyes, A.   +12 more
core   +1 more source

Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients [PDF]

, 2021
Turner syndrome (TS) is a genetic disorder in females with X Chromosome monosomy associated with highly variable clinical features, including premature primary gonadal failure leading to ovarian dysfunction and infertility.
Tamas Revay, Naira Caroline Godoy Pieri, Ester Silveira Ramos, Aline Fernanda de Souza, Meirelles, Flavio, King, Willian Allan, Pieri, Naira Caroline Godoy, King, Willian, Bressan, Fabiana, Haddad, Simone, Willian Allan King, Ramos, Ester Silveira, Botigelli, Ramon, Meirelles, Flavio Vieira, Covas, Dimas Tadeu, Simone Kashima Haddad, Pieri, Naira, Ramos, Ester, Souza, Aline Fernanda de, Flavio Vieira Meirelles, de Souza, Aline, Botigelli, Ramon Cesar [UNESP], Haddad, Simone Kashima, Revay, Tamas, Bressan, Fabiana Fernandes, Fabiana Fernandes Bressan, Covas, Dimas, Ramon Cesar Botigelli, Dimas Tadeu Covas   +28 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Testicular development in mice lacking receptors for follicle stimulating hormone and androgen [PDF]

, 2012
Post-natal testicular development is dependent on gonadotrophin and androgen stimulation. Follicle stimulating hormone (FSH) acts through receptors (FSHR) on the Sertoli cell to stimulate spermatogenesis while androgens promote testis growth through ...
Abel, M., Ana Monteiro, Abel Margaret, Margaret Abel, Peter J. O’Shaughnessy (171628), O’Shaughnessy Peter J., Monteiro, A., O'Shaughnessy, P.J., Ana Monteiro (171632), Peter J O'Shaughnessy, Margaret Abel (171636), Monteiro Ana   +11 more
core   +1 more source

Sex-specific isolation and propagation of human premeiotic fetal germ cells and germ cell-like cells

, 2021
The second trimester of human development is marked by asynchronous gonadal development hampering the isolation of homogenous populations of early and late fetal germ cells (FGCs).
Sutter, P. de, Mishra, S., Mishra, Swati, Susana M. Chuva De Sousa Lopes, De Sutter, Petra, Jasin Taelman, Petra De Sutter, Lopes, S.M.C.D., Swati Mishra, Boel, Annekatrien, Chang, Yolanda W., Björn Heindryckx, Yolanda W. Chang, Taelman, J., Boel, A., Chang, Y.W., Chuva de Sousa Lopes, Susana Marina, Taelman, Jasin, Annekatrien Boel, Heindryckx, Björn, Heindryckx, B.   +20 more
core   +1 more source