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The germline of Caenorhabditis elegans derives from a single founder cell, the germline blastomere P(4). P(4) is the product of four asymmetric cleavages that divide the zygote into distinct somatic and germline (P) lineages. P(4) inherits a specialized cytoplasm ("germ plasm") containing maternally encoded proteins and RNAs.
Jennifer T, Wang, Geraldine, Seydoux
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Of Stem Cells and Germ Cells [PDF]
ContentsStem cells have an intrinsic capacity to selfârenew and can differentiate to at least one specialized cell type. Different types of stem cells exist that can be culturedin vitro. The identity of the stem cells is marked by their origin and differentiation potential.
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BackgroundSOX17 has been identified as a critical factor in specification of human primordial germ cells, but whether SOX17 regulates development of germ cells after sex differentiation is poorly understood. MethodsWe collected specimens of gonadal ridge
Ying-Yi Luo +9 more
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Chicken primordial germ cells isolated from embryonic blood were cultured in vitro on feeder cells derived from the gonads of 7-day incubated embryos. Primordial germ cells were proliferated about 13 times during the 4 day culture period on the feeder ...
Mitsuru Naito +5 more
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Primary Culture System for Germ Cells from Caenorhabditis elegans Tumorous Germline Mutants
The Caenorhabditis elegans germ line is an important model system for the study of germ stem cells. Wild-type C. elegans germ cells are syncytial and therefore cannot be isolated in in vitro cultures. In contrast, the germ cells from tumorous mutants can
Alexandra Vagasi +3 more
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The objective of this study was to understand germ cell renewal and differentiation in the Yesso scallop Mizuhopecten yessoensis throughout its reproductive cycle.
Mariia Mokrina +4 more
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Tre1, a G protein-coupled receptor, directs transepithelial migration of Drosophila germ cells.
In most organisms, germ cells are formed distant from the somatic part of the gonad and thus have to migrate along and through a variety of tissues to reach the gonad.
Prabhat S Kunwar +4 more
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On the development of extragonadal and gonadal human germ cells
Human germ cells originate in an extragonadal location and have to migrate to colonize the gonadal primordia at around seven weeks of gestation (W7, or five weeks post conception).
A. Marijne Heeren +8 more
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Cell cycle regulation for meiosis in mammalian germ cells
In mouse fetal gonads, germ cell development is accompanied by changes in cell cycle mode in response to external signals and intrinsic mechanisms of cells.
Ryuki SHIMADA, Kei-ichiro ISHIGURO
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Germ Cell Derivation from Pluripotent Stem Cells for Understanding In Vitro Gametogenesis
Assisted reproductive technologies (ARTs) have developed considerably in recent years; however, they cannot rectify germ cell aplasia, such as non-obstructive azoospermia (NOA) and oocyte maturation failure syndrome. In vitro gametogenesis is a promising
Tae-Kyung Hong +3 more
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