Results 181 to 190 of about 77,179 (233)
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The role of anti-Müllerian hormone in gonadal development
Molecular and Cellular Endocrinology, 1998Anti-Müllerian (AMH), a member of the transforming growth factor beta produced by immature Sertoli cells and, to a lesser degree, by granulosa cells from birth to the end of reproductive life, does not affect gonadal determination but has a negative effect upon gonadal development in both sexes.
N, Josso +4 more
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SF1 in the Development of the Adrenal Gland and Gonads
Hormone Research in Paediatrics, 2003SF1 (steroidogenic factor-1; NR5A1) is an orphan nuclear receptor that is expressed in the adrenal gland, gonads, spleen, ventromedial hypothalamus and pituitary gonadotroph cells. Combined approaches of targeted mutagenesis in mice and examination of the effects of naturally occurring mutations in humans have clarified the role of SF1 in ...
Gokhan, Ozisik +3 more
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Role of gonadal hormones in development of the sexual phenotypes
Human Genetics, 1981Male and female embryos develop in an identical fashion during the initial portion of gestation. If the indifferent gonad differentiates into an ovary (or if no gonad is present), a female phenotype is formed. Male phenotypic differentiation, however, requires the presence of an endocrinologically active testis.
J D, Wilson +3 more
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Transcriptional Development of the Hypothalamic-Pituitary-Gonadal Axis
2002Unlike other hypothalamic neuropeptide-producing cells, GnRH neurons do not arise from the developing basal forebrain. They originate in the olfactory placode in mammals and migrate across the nasal cavity and cribiform plate into the forebrain (1, 2).
Sally Radovick +4 more
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Expression of Dax-1 during gonadal development of the frog
Gene, 2001Dax-1, a member of the nuclear hormone receptor superfamily of transcription factors, is known to be involved in gonadal development in mammals. To date, Dax-1 has only been isolated in reptiles, birds and mammals. The expression of Dax-1 is down-regulated in the developing testis, but persists in the ovary of mice (Swain et al., Nat. Genet.
J, Sugita, M, Takase, M, Nakamura
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The Development of Cyclic Pituitary—Gonadal Function in Adolescent Females
The Journal of Clinical Endocrinology & Metabolism, 1973ABSTRACT Serum concentrations of FSH, LH, estradiol, progesterone and testosterone were measured at 2–3-day intervals for 35 days in 1 prepubertal girl, 3 pubertal premenarchal girls, 1 girl at menarche and 2 girls who were 6 and 9 months postmenarche. No hormone rhythms were seen before puberty.
J S, Winter, C, Faiman
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Methods for the Study of Gonadal Development
2016Current knowledge on gonadal development and sex determination is the product of many decades of research involving a variety of scientific methods from different biological disciplines such as histology, genetics, biochemistry, and molecular biology.
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The Curious World of Gonadal Development in Mammals
2016The distinct sex phenotypes of male and female hinge on the development of the fetal gonads as testes or ovaries, in turn, regulated by the molecular genetic machinery of sex determination. Here, I discuss five aspects of mammalian gonadal development that distinguish it from other examples of organogenesis, and continue to surprise and fascinate.
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Androstenedione metabolism in the indifferent stage of bovine gonad development
Journal of Experimental Zoology, 1995AbstractSuspensions of cells obtained from genital ridges and gonads of bovine embryos of 1.0‐3.4 cm in crown‐rump (C‐R) length were used for studies of the metabolism of radiolabeled exogenous steroid precursor. Tritiated androstenedione was employed as precursor and the final products of their metabolism were evaluated after separation by thin‐layer ...
M A, Juárez-Oropeza +4 more
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Profiles of Gonadal Gene Expression in the Developing Bovine Embryo
Sexual Development, 2009Our current understanding of the molecular basis of sex determination and gonadal development in humans is mostly an extrapolation of knowledge gained from studies in the mouse. However, the timing of gene expression in the mouse is unusual among mammals, and it is therefore important that data from other models are also available to help elucidate ...
Ross, D.G.F. +4 more
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