Plans for the development of cryogenic engines for space exploration [PDF]
The NASA Lewis Research Center (LeRC) is conducting a broad range of basic research and focused technology development activities in both aeronautical and space propulsion. By virtue of the successful conduct of these programs, LeRC is strongly qualified
Aukerman, Carl A. +2 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
İmar Planlarının Hazırlanma Süreci ve Peyzaj Mimarlığı Disiplini Açısından Karşılaşılan Sorunlar
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2018 İmarplanları; fiziksel çevreyi sağlıklı bir yapıya kavuşturmak, yatırımların yerseçimlerini ve gelişme eğilimlerini yönlendirmek ve toprağın kullanma dengesinien rasyonel biçimde belirlemek üzere hazırlanan planlardır.
Büşra Ezenci
doaj
Insights Gained into the Use of Individual Development Plans as a Framework for Mentoring NIH Postbaccalaureate Research Education Program (PREP) Trainees. [PDF]
J Chem Educ, 2022 Hardy TM +3 more
europepmc +1 more source
NASAs Plans for Development of Standards for Additive Manufactured Components [PDF]
There are currently no NASA standards providing specific design and construction requirements for certification of additively manufactured parts. Several international standards organizations are developing standards for additive manufacturing; however ...
Russell, Richard W.
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Common Commentary on Paediatric Oncology Drug Development Published: Another Step in Optimising Global Regulatory Coordination of Paediatric Development Plans. [PDF]
Ther Innov Regul Sci, 2021 Karres D +7 more
europepmc +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Public Support for the Development of Organic Farming in Europe [PDF]
, 1999 The growth of organic farming in the European Union and the reasons for supporting organic farming are examined in the context of policy support for organic farming under EC Reg.
Lampkin, Dr Nicolas
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source