Results 111 to 120 of about 2,858,598 (299)

Preclinical and Clinical Characteristics of the Trichuricidal Drug Oxantel Pamoate and Clinical Development Plans: A Review. [PDF]

open access: yesDrugs, 2021
Palmeirim MS   +5 more
europepmc   +1 more source

Book Review: Archeology in the Eastern Planning Region, Texas: A Planning Document [PDF]

open access: yes, 1996
With the passage of the National Historic Preservation Act in 1966 and ensuing regulatory guidelines, a mandate for the development of The State Historic Preservation Plan was clearly established. During the late 1960s and the 1970s, because of limited
Brooks, Robert L.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

REGIONAL DEVELOPMENT IN ROMANIA: EXPERIENCES IN THE EUROPEAN INTEGRATION PROCESS [PDF]

open access: yes
Sustainable development builds the vision on the future and it is shaped in goals and appropriate actions for all levels of approach. The progress towards this future necessitates the definition of intermediary plans for objectives and targets that allow
Carmen Valentina RADULESCU, Florina BRAN
core  

Middleware for managing a large, heterogeneous programmable network [PDF]

open access: yes, 2002
The links between BTexact Technologies and the Department of Computing Science at University College London are becomingincreasingly beneficial for the development of the middleware area for the management of programmable networks.
Hughes, A.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Development Plans and Life Plans: Knowledge Sharing?

open access: yesMundo Amazónico, 2010
This article explores the possibilities of establishing knowledge sharing between governmental development plans and the “life plans” (planes de vida) made by indigenous organizations, in particular the life plan of the Asociación de Autoridades ...
Juan José Vieco Albarracín
doaj  

Ground Systems Development Environment (GSDE) software configuration management [PDF]

open access: yes
This report presents a review of the software configuration management (CM) plans developed for the Space Station Training Facility (SSTF) and the Space Station Control Center.
Church, Victor E.   +3 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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