Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
What Are Public Health Agencies Planning for Workforce Development? A Content Analysis of Workforce Development Plans of Accredited Public Health Departments. [PDF]
Yeager VA +8 more
europepmc +1 more source
IDB News: Vol. 1, no. 6, July 1974
IDB News is a monthly publication of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Proposal of a Multi-Criteria Model for the Evaluation of Territorial Development Plans: An Application in Chile's Lagging Areas. [PDF]
Arancibia-Carvajal S +3 more
europepmc +1 more source
IDB News: Vol. 3, no. 11, December 1976
IDB News is a monthly publication of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Are local development plans mainstreaming climate-smart agriculture? A mixed-content analysis of medium-term development plans in semi-arid Ghana. [PDF]
Diko SK +5 more
europepmc +1 more source
IDB News: Vol. 3, no. 3, April 1976
IDB News is a monthly publication of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core +1 more source
BackgroundNoncommunicable diseases (NCDs) account for about 73.7% of deaths across the Gulf Cooperation Council (GCC). GCC states have adopted long-term national development visions to provide a coherent framework for economic diversification.
Rasha Alfawaz +10 more
doaj +1 more source

