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Background: Curriculum changes in Indonesia require teachers to prepare learning resources that can train students' important skills, especially critical thinking and creative thinking skills. Objectives: produce PJBL-STEM teaching module to improve the
Lilis Sundari, P. Paidi, Nourma Yulita
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The Development of Web-based Instructional Media for Teaching Wave Physics on Android Mobile
This study aims to develop an Android app to support learning activities consisting of mobile applications and web server applications. Mobile applications have two applications: teacher apps and student applications, while web server applications are ...
Bintang Ronauli Simanjuntak +2 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
RESEARCH REPORT ON THE NATIONAL DEVELOPMENT AGENCY [PDF]
This Report attempts to examine how an institution like the NDA, which was established to meet the short-term needs of NGOs in development and the long-term need to promote partnership between government and these organisations, is assisting in creating ...
core
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Sari Embun Lake is one of the areas in Tanah Laut Regency with various fish species that have potential as supporting material for local potential-based animal ecology courses.
Nur Alita Yulianti +2 more
doaj +1 more source
Current state of development of Eurocomprehension research [PDF]
"Eurocomprehension" is the term used to describe European intercomprehension in Europe’s three major language families, the Romance, the Slavic and the Germanic. The aim of eurocomprehension is to achieve multilingualism conforming to EU language policy
Klein, Horst G.
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

