Results 81 to 90 of about 10,824,649 (308)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
InfinityThe 4C skills (communication, collaboration, creativity, critical thinking) represent essential competencies for 21st-century students. Multiliteracy contexts play a crucial role in supporting learning, while assessment contributes significantly to ...
Edy Setiyo Utomo +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Ecoregional Research for Development
, 2007 Publisher Summary This chapter focuses on the subject of ecoregional research for development. The character of international agricultural research has changed profoundly in the last decades of the twentieth century. This can be illustrated by developments within the Consultative Group on International Agricultural Research (CGIAR).
Bouma, J. +10 more
openaire +4 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
, 2013 The Development Research Uptake in Sub-Saharan Africa (DRUSSA) Programme “Platform 2013” publication provides a round-up of current evidence-based development research which can be used as a platform towards public policy influence.
Development Research Uptake in Sub-Saharan Africa (DRUSSA)
core
From Intervention to Empowerment: A New Approach to Assisting SMEs in Latin America: Regulation, Procurement, and Dispute Resolution [PDF]
, 2008 This paper outlines some of the issues that affect small and medium sized enterprises (SMEs) in three areas: regulation, procurement, and dispute resolution. The work presented herein is part of the Bank\u27s most recent efforts to develop new approaches
Inter-American Development Bank
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Journal of Investigative Surgery, 2011 After the interest in surgical research, developing the research idea is of fundamental importance because without it we can not have research. Where do the research ideas come from then? Is there any better way to improve our ability to generate research ideas? Where do they come from? What are the factors that stimulate the research idea? Anything we
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source