Results 131 to 140 of about 2,013,928 (265)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

[Development strategy of stomatology industry]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Yu G.
europepmc   +1 more source

Research and development strategy for biodegradable magnesium-based vascular stents: a review. [PDF]

Biomater Transl, 2021
Niu J, Huang H, Pei J, Jin Z, Guan S, Yuan G.   +5 more
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

A novel EST-SSR fingerprint database development strategy for accurate identification of asparagus cultivars. [PDF]

BMC Plant Biol
Yi ZH, Wang Y, Song HX, Zhao J, Mao LP.
europepmc   +1 more source

Development Strategy of Intelligent Digital Library without Human Service in the Era of "Internet +".

Comput Intell Neurosci, 2022
Wang H, Ding J.
europepmc   +1 more source

Use of Real-World Evidence to Drive Drug Development Strategy and Inform Clinical Trial Design. [PDF]

Clin Pharmacol Ther, 2022
Dagenais S, Russo L, Madsen A, Webster J, Becnel L.   +4 more
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Review of advanced research on swine <i>Actinobacillus pleuropneumoniae</i> vaccine development strategy. [PDF]

Front Immunol
Tesfaye AB, Han R, Tao Z, You L, Zhu J, Gao P, Fu L, Chu Y.   +7 more
europepmc   +1 more source

The key issues and development strategy of Chinese Classical Formulas pharmaceutical preparations. [PDF]

Chin Med, 2021
Luo H, Chen H, Liu C, Zhang S, Vong CT, Tan D, Dai Y, Wang Y, Chen S.   +8 more
europepmc   +1 more source