Results 141 to 150 of about 2,597,153 (267)

Use of Real-World Evidence to Drive Drug Development Strategy and Inform Clinical Trial Design. [PDF]

Clin Pharmacol Ther, 2022
Dagenais S, Russo L, Madsen A, Webster J, Becnel L.   +4 more
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A novel EST-SSR fingerprint database development strategy for accurate identification of asparagus cultivars. [PDF]

BMC Plant Biol
Yi ZH, Wang Y, Song HX, Zhao J, Mao LP.
europepmc   +1 more source

Development Strategy of Intelligent Digital Library without Human Service in the Era of "Internet +".

Comput Intell Neurosci, 2022
Wang H, Ding J.
europepmc   +1 more source

Determining the Development Strategy and Suited Adoption Paths for the Core Competence of Shared Decision-Making Tasks through the SAA-NRM Approach. [PDF]

Int J Environ Res Public Health, 2022
Yu SF, Wang HT, Chang MW, Cheng TT, Chen JF, Lin CL, Yu HT.   +6 more
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Review of advanced research on swine <i>Actinobacillus pleuropneumoniae</i> vaccine development strategy. [PDF]

Front Immunol
Tesfaye AB, Han R, Tao Z, You L, Zhu J, Gao P, Fu L, Chu Y.   +7 more
europepmc   +1 more source

The key issues and development strategy of Chinese Classical Formulas pharmaceutical preparations. [PDF]

Chin Med, 2021
Luo H, Chen H, Liu C, Zhang S, Vong CT, Tan D, Dai Y, Wang Y, Chen S.   +8 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Interlayer Interference Analysis and Layered Development Strategy in CO₂ Miscible Flooding of Reverse-Rhythm Reservoirs. [PDF]

ACS Omega
Wei J, Yu H, Gao M, Lang X, Zhao B, Liu W, Yin H.   +6 more
europepmc   +1 more source