Results 131 to 140 of about 2,597,153 (267)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Synergistic Inhibitor Development Strategy Against Human UDP-Galactose-4-Epimerase. [PDF]

open access: yesAngew Chem Int Ed Engl
Browne WM   +22 more
europepmc   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Probiotic Development Strategy Centered on Stability and Regulatory Considerations. [PDF]

open access: yesCompr Rev Food Sci Food Saf
Kim H   +5 more
europepmc   +1 more source

Research and development strategy for biodegradable magnesium-based vascular stents: a review. [PDF]

open access: yesBiomater Transl, 2021
Niu J   +5 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

[Development strategy of stomatology industry]. [PDF]

open access: yesBeijing Da Xue Xue Bao Yi Xue Ban
Yu G.
europepmc   +1 more source

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