Results 71 to 80 of about 37,171 (198)

Development of Domestic and Overseas Liner Drilling Technology

open access: yesShiyou jixie, 2018
Liner drilling can effectively address the drilling problems such as narrow drilling boundary, tight hole, well loss and wellbore instability, and reduce drilling time and operating cost, which is especially suitable for deepwater drilling and depleted ...
Wu Jinxia, Zhang Rui
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Technology Status and Development Trend of Wind Turbine Generation System

open access: yesKongzhi Yu Xinxi Jishu, 2013
The development status of global wind power generation is illustrated and the status of wind turbine R&D technology in China and the technology gaps between China and foreign countries are analyzed.
ZHANG Xinning
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Key Technology and Development Trend of Permanent Magnet Motor Traction System for Rail Transit

open access: yes机车电传动, 2018
The characteristics and advantages of permanent magnet motor traction system in rail transit were introduced. The development status of permanent magnet motor traction system in rail transit at home and abroad was summarized.
FENG Jianghua
doaj  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Analysis on the geological structure and characteristic of Baige landslide in Jinshajiang tectonic melange belt

open access: yesShuiwen dizhi gongcheng dizhi
The Baige landslide is located in the Jinshajiang tectonic melange belt with extremely complex geological conditions. Understanding the geological structure features of the Baige area is of crucial importance for subsequent disaster risk assessment ...
Shilin ZHANG   +5 more
doaj   +1 more source

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