Results 81 to 90 of about 37,171 (198)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Development trend and typical applications of industrial big data

open access: yesDianxin kexue, 2016
The concept and characteristics of industrial big data were introduced,and its development trend was discussed.It meant that industrial big data cluld be widely used in the whole production process in manufacturing enterprises.According to application ...
Mingfeng HUANG
doaj  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Wellhead Tieback Technology for Shallow Sea Well under Integrated Exploration-development Strategy

open access: yesShiyou jixie, 2018
According to relevant laws and regulations, at the end of well life, the exploratory well will either be permanently abandoned or temporary abandoned. The permanent abandonment requirement is stricter than the temporary abandonment.
Huo Hongbo   +6 more
doaj  

Biomimetic technologies for drill rods: Advances in research and development trends

open access: yesMeitian dizhi yu kantan
Significance Drill rods are recognized as core tools in drilling engineering, and their performance exerts a significant influence on drilling efficiency and safety.
Chuanliu WANG, Pei JU
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Issue Analysis of Large Scale Fracturing Equipment Application and Its Development Trend

open access: yesShiyou jixie, 2017
In the process of domestic shale gas development, large-scale fracturing equipment have common applications issues like low power utilization and unreasonable equipment application.
Wu Hanchuan
doaj  

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