Results 91 to 100 of about 1,273,570 (277)

Developmental Disabilities timeline: a history of developmental disability-related policy : Benton County Developmental Diversity Program 50th anniversary (1971-2021)

open access: yes, 2021
Presents an inclusive overview of international, federal, state, and local health and disability public policy prepared to commemorate the 50th anniversary of the Benton County Developmental Diversity Program.Caption title.This archived document is ...

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Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Developmental disabilities quarterly

open access: yes, 2002
Spring 2001-; Description based on: Spring 2001; title from PDF caption (viewed on June 16, 2008); "Publication of the Ohio Developmental Disabilities Council bringing disability issues and accomplishments to the attention of Ohioans."; Harvested from ...
Ohio Developmental Disabilities Council.
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The Importance of Developmental Assets to the Five Cs of Positive Youth Development among Norwegian Youth [PDF]

open access: yes, 2022
Positive youth development (PYD) focuses on the positive assets of young people. The PYD framework views young people as resources to be developed.
Mesfin, Ghenet Seyoum
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Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Developmental assets as predictors of Albanian adolescents’ life satisfaction

open access: yesRevista de Psicología
This study examined the relationship between Positive Youth Development (PYD) Internal and External assets and life satisfaction among Albanian adolescents.
Eglantina Dervishi   +2 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Presidential Commission on Holocaust Assets in the United States

open access: yes, 2001
To present a thorough historical record of the collection and disposition of the assets of Holocaust victims that came into the possession or control of the Government of the United States.
Presidential Commission on Holocaust Assets in the United States
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