Results 61 to 70 of about 1,273,570 (277)

Ohio Early Intervention COVID-19 guidelines

, 2020
"March 12, 2020."Early intervention timelines -- Using technology -- Best practicesThe Ohio Department of Developmental Disabilities (DODD) provides the following guidelines to support Early Intervention (EI) service providers in carrying out the ...
Ohio. Department of Developmental Disabilities
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Supported employment services for individuals experiencing intellectual and developmental disabilities (I/DD) [PDF]

, 2016
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on July 6, 2016)."The Office ...

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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Socio-emotional and personal development competencies as assets facilitating psychosocial adaptation in socially vulnerable secondary school students

Frontiers in Psychology
Fostering positive developmental assets in the school student population could improve individuals' psychological adjustment processes and personal wellbeing. In view of the above, employing a non-probability selective, cross-sectional design, this study
Victor Manuel Pardo, Susana De La Ossa, Manuel Noreña   +2 more
doaj   +1 more source

Contextual and Individual Predictors of Bullying and Victimization in Slovenia: Positive Youth Development Perspective

Erebea, 2020
Bullying and victimization pose a serious risk for youth optimal development due to numerous negative short- and long-term consequences. One of the models with a focus on adolescents that can serve as a theoretical framework in designing prevention and ...
Ana Kozina, Tina Pivec
doaj   +1 more source

Texas Council for Developmental Disabilities Annual Report [PDF]

, 1999
Report for the expenditures and projects pursued by the Texas Planing for Developmental Disabilities during the fiscal ...
Texas Council for Developmental Disabilities
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Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Content analysis of developmental assets in HIV/AIDS message framing [PDF]

, 2011
Dissertation (MEd)--University of Pretoria, 2010.The purpose of this qualitative study was to explore and describe how the developmental asset framework could be used to conceptualise HIV/AIDS message framing.

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