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Advocating developmental biology [PDF]
Developmental biology is a discipline with a long and rich history, a vibrant and diverse present, and a future of tremendous potential. The field has had enormous impact beyond its own boundaries, for example providing many key concepts for medical research and laying the foundations for ...
Aidan Maartens +3 more
openaire +2 more sources
miR-29cb2 promotes angiogenesis and osteogenesis by inhibiting HIF-3α in bone
Summary: Coordination between osteogenesis and angiogenesis is required for bone homeostasis. Here, we show that miR-29cb2 is a bone-specific miRNA and plays critical roles on angiogenesis-osteogenesis coupling during bone remodeling.
Liping Ouyang +12 more
doaj +1 more source
Developmental noise—which level may vary within a certain backlash allowed by natural selection—is a reflection of the state of a developing system or developmental stability.
V. Zakharov, E. Shadrina, I. Trofimov
semanticscholar +1 more source
Label-free optical imaging in developmental biology [Invited].
Application of optical imaging in developmental biology marks an exciting frontier in biomedical optics. Optical resolution and imaging depth allow for investigation of growing embryos at subcellular, cellular, and whole organism levels, while the ...
Shang Wang, I. Larina, K. Larin
semanticscholar +1 more source
Protocol for isolation and ATAC-seq library construction of zebrafish red blood cells
Summary: Understanding chromatin dynamics in red blood cells (RBCs) is critical for exploring the differentiation process and homeostasis maintenance during erythropoiesis.
Yanyan Ding, Feng Liu
doaj +1 more source
Synthetic Developmental Biology: Understanding Through Reconstitution.
Reconstitution is an experimental strategy that seeks to recapitulate biological events outside their natural contexts using a reduced set of components.
Gavin Schlissel, Pulin Li
semanticscholar +1 more source
A lncRNA perspective into (re)building the heart
Our conception of the human genome, long focused on the 2% that codes for proteins, has profoundly changed since its first draft assembly in 2001. Since then, an unanticipatedly expansive functionality and convolution has been attributed to the majority ...
Stefan Frank +4 more
doaj +1 more source
Non-muscle myosin II drives critical steps of nematocyst morphogenesis
Summary: Nematocysts are generated by secretion of proteins into a post-Golgi compartment. They consist of a capsule that elongates into a long tube, which is coiled inside the capsule matrix and expelled during its nano-second discharge deployed for ...
Niharika Garg +12 more
doaj +1 more source
Acknowledgement to Reviewers of Journal of Developmental Biology in 2015
The editors of Journal of Developmental Biology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015. [...]
Journal of Developmental Biology Editorial Office
doaj +1 more source
X-Linked Huwe1 Is Essential for Oocyte Maturation and Preimplantation Embryo Development
Summary: HUWE1 is a HECT-domain ubiquitin E3 ligase expressed in various tissues. Although HUWE1 is known to promote degradation of the tumor suppressor p53, given a growing list of its substrates, in vivo functions of HUWE1 remain elusive.
Alaa A. Eisa +11 more
doaj +1 more source

