Results 1 to 10 of about 492,391 (271)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Harmony in chaos: understanding cancer through the lenses of developmental biology. [PDF]

Mol Oncol
Van Lent J, Baggiolini A.
europepmc   +1 more source

Mathematical model and genomics construction of developmental biology patterns using digital image technology. [PDF]

Front Genet, 2022
Ni S, Chen F, Chen G, Yang Y.
europepmc   +1 more source

Developmental biology of sea urchins

, 1997

openalex   +1 more source

Etiology and Morphogenesis of Congenital Heart Disease: Twenty Years of Progress in Genetics and Developmental Biology [PDF]

, 2001

openalex   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

The developmental biology of Charnia and the eumetazoan affinity of the Ediacaran rangeomorphs. [PDF]

Sci Adv, 2021
Dunn FS, Liu AG, Grazhdankin DV, Vixseboxse P, Flannery-Sutherland J, Green E, Harris S, Wilby PR, Donoghue PCJ.   +8 more
europepmc   +1 more source

Developmental cheating and the evolutionary biology of Dictyostelium and Myxococcus

, 2000
Dee N. Dao, Richard H. Kessin, Herbert L. Ennis   +2 more
openalex   +1 more source

Critical steps in the early evolution of the isocortex: Insights from developmental biology [PDF]

, 2002
Francisco Aboitiz, Juan F. Montiel, Javier Sánchez López   +2 more
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source