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Developmental biology of hematopoiesis [PDF]
The cellular and environmental regulation of hematopoiesis has been generally conserved throughout vertebrate evolution, although subtle species differences exist. The factors that regulate hematopoietic stem cell homeostasis may closely resemble the inducers of embryonic patterning, rather than the factors that stimulate hematopoietic cell ...
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Progresses in developmental biology [PDF]
Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China E-mail: wujr@sibs.ac.cn Developmental biology is one of the most advanced areas in life science. JMCB has published several collections reporting the research findings that advance our understanding of the ...
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Summary: Activity-dependent calcium signals in developing muscle play a crucial role in neuromuscular junction (NMJ) formation. However, its downstream effectors and interactions with other regulators of pre- and postsynaptic differentiation are poorly ...
Mehmet Mahsum Kaplan +1 more
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Developmental biology of lichens [PDF]
SUMMARYLichen‐forming fungi are a large, taxonomically diverse group of nutritional specialists which acquire fixed carbon from a population of minute green algal or cyanobacterial cells. Mycobionts of foliose or fruticose lichens differ from the rest of the fungi by expressing morphologically and anatomically complex symbiotic phenotypes.
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A newly emerged seedling, given light and water, but no external source of minerals, uses its internal mineral nutrient reserves effectively for an early establishment.
T. Mandizvo, A.O. Odindo
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Apicosome: Newly identified cell-type-specific organelle in mouse cochlear and vestibular hair cells
Summary: Cochlear and vestibular hair cells are highly specialized sensory receptors for hearing and balance. Here, we report a serendipitous identification of a hair-cell-specific organelle in neonatal mouse inner ear, which we name “apicosome.” The ...
Xiaofen Li +9 more
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The emerging models of human embryonic stem cell (hESC) self-organizing organoids provide a valuable in vitro platform for studying self-organizing processes that presumably mimic in vivo human developmental events. Here we report that through a chemical
Yijie Geng, Bradley Feng
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Sox9 regulates melanocytic fate decision of adult hair follicle stem cells
Summary: The bulge of hair follicles harbors Nestin+ (neural crest like) stem cells, which exhibit the potential to generate various cell types including melanocytes.
Isabel Stüfchen +6 more
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Increasing Diversity in Developmental Biology
The demographic profile of the scientific and biomedical workforce in the United States does not reflect the population at large (https://ncses.nsf.gov/pubs/nsf21321/data-tables; www.census.gov), raising concerns that there will be too few trained ...
Graciela A. Unguez +3 more
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Chromosome instability and aneuploidies occur very frequently in human embryos, impairing proper embryogenesis and leading to cell cycle arrest, loss of cell viability, and developmental failures in 50–80% of cleavage-stage embryos.
Gennadi Glinsky +7 more
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