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Embryological Consideration of Dural AVFs in Relation to the Neural Crest and the Mesoderm [PDF]

Neurointervention, 2019
Intracranial and spinal dural arteriovenous fistulas (DAVFs) are vascular pathologies of the dural membrane with arteriovenous shunts. They are abnormal communications between arteries and veins or dural venous sinuses that sit between the two sheets of ...
Michihiro Tanaka
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Hox Proteins in the Regulation of Muscle Development

Frontiers in Cell and Developmental Biology, 2021
Hox genes encode evolutionary conserved transcription factors that specify the anterior–posterior axis in all bilaterians. Being well known for their role in patterning ectoderm-derivatives, such as CNS and spinal cord, Hox protein function is also ...
Gabriela Poliacikova, Corinne Maurel-Zaffran, Yacine Graba, Andrew J. Saurin   +3 more
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Stem/progenitor cells in the developing human lung

Journal of Pediatric and Neonatal Individualized Medicine, 2016
Human lungs are composed of more than 40 cell types. The lung is classified as a “conditionally renewing” tissue and is able of a quick response to cellular damage thanks to the presence of multiple stem/progenitor cells.
Daniela Fanni, Margherita Fanos, Clara Gerosa, Flaviana Cau, Erika Pisu, Peter Van Eyken, Rossano Ambu   +6 more
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Manipulation of cell:cell contacts and mesoderm suppressing activity direct lineage choice from pluripotent primitive ectoderm-like cells in culture. [PDF]

PLoS ONE, 2009
In the mammal, the pluripotent cells of embryo differentiate and commit to either the mesoderm/endoderm lineages or the ectoderm lineage during gastrulation.
James N Hughes, Jennifer M Washington, Zhiqiang Zheng, Xiuwen K Lau, Charlotte Yap, Peter D Rathjen, Joy Rathjen   +6 more
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Brachyury co-operates with polycomb protein RYBP to regulate gastrulation and axial elongation in vitro

Frontiers in Cell and Developmental Biology
Early embryonic development is a complex process where undifferentiated cells lose their pluripotency and start to gastrulate. During gastrulation, three germ layers form, giving rise to different cell lineages and organs.
Lilla Kokity, Lilla Kokity, Zsolt Czimmerer, Bernadett Benyhe-Kis, Bernadett Benyhe-Kis, Anna Poscher, Anna Poscher, Emese Belai, Emese Belai, Gábor Steinbach, Zoltan Lipinszki, Zoltan Lipinszki, Melinda Katalin Pirity   +12 more
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Location, Location, Location: Signals in Muscle Specification

Journal of Developmental Biology, 2018
Muscles control body movement and locomotion, posture and body position and soft tissue support. Mesoderm derived cells gives rise to 700 unique muscles in humans as a result of well-orchestrated signaling and transcriptional networks in specific time ...
Chih-Ning Chang, Chrissa Kioussi
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Alternative Ways to Obtain Human Mesenchymal Stem Cells from Embryonic Stem Cells

Cells
Differentiation approaches to obtain mesenchymal stem cells (MSCs) have gradually developed over the last few decades. The problem is that different protocols give different MSC types, making further research difficult.
Nikita Onyanov, Olga Glazova, Nawar Sakr, Tatyana Krokunova, Julia Krupinova, Pavel Volchkov   +5 more
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An unexpected role of IL10 in mesoderm induction and differentiation from pluripotent stem cells: Implications in zebrafish angiogenic sprouting, vascular organoid development, and therapeutic angiogenesis

European Journal of Cell Biology
Mesoderm induction is a crucial step for vascular cell specification, vascular development and vasculogenesis. However, the cellular and molecular mechanisms underlying mesoderm induction remain elusive.
Kaiyuan Niu, Chengxin Zhang, Chenxin Liu, Wei Wu, Yi Yan, Ancheng Zheng, Silin Liu, Zhenning Shi, Mei Yang, Wen Wang, Qingzhong Xiao   +10 more
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Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3

Stem Cell Reports, 2017
Mesoderm derived from human embryonic stem cells (hESCs) is a major source of the mesenchymal stem/stromal cells (MSCs) that can differentiate into osteoblasts and chondrocytes for tissue regeneration.
Yongxin Yu, Peng Deng, Bo Yu, John M. Szymanski, Tara Aghaloo, Christine Hong, Cun-Yu Wang   +6 more
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Developmental Mechanism of Limb Field Specification along the Anterior–Posterior Axis during Vertebrate Evolution

Journal of Developmental Biology, 2016
In gnathostomes, limb buds arise from the lateral plate mesoderm at discrete positions along the body axis. Specification of these limb-forming fields can be subdivided into several steps.
Mikiko Tanaka
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