Results 1 to 10 of about 315,194 (170)

LncRNA GAS5-hnRNPK axis inhibited ovarian cancer progression via inhibition of AKT signaling in ovarian cancer cells

open access: yesDiscover Oncology, 2023
Background The incidence of ovarian cancer ranks third among gynecologic malignancies, but the mortality rate ranks first. Methods The expression of GAS5 is low in ovarian cancer and is associated with the low survival of ovarian cancer patients ...
Te Zhang   +18 more
doaj   +1 more source

NSUN2 alleviates doxorubicin-induced myocardial injury through Nrf2-mediated antioxidant stress

open access: yesCell Death Discovery, 2023
Doxorubicin (DOX) is a commonly used antitumor drug, but its application has been limited because of its strong cardiac damage. This study aims to explore the role of NSUN2 in DOX-induced heart injury.
Yi Wang   +13 more
doaj   +1 more source

Embryonic stem cells [PDF]

open access: yesThe Journal of Pathology, 2002
AbstractThe capacity of embryonic stem cells for virtually unlimited self‐renewal and differentiation capacity has opened up the prospect of widespread applications in biomedical research and regenerative medicine. For the latter, the cells provide hope that it will be possible to overcome the problems of donor tissue shortage and also, by making the ...
Anne E, Bishop   +2 more
openaire   +2 more sources

Embryonic stem cells [PDF]

open access: yesCell Proliferation, 2004
Abstract.  Embryonic stem cells have huge potential in the field of tissue engineering and regenerative medicine as they hold the capacity to produce every type of cell and tissue in the body. In theory, the treatment of human disease could be revolutionized by the ability to generate any cell, tissue, or even organ, ‘on demand’ in the laboratory. This
H J, Rippon, A E, Bishop
openaire   +2 more sources

Effects of Luteolin-7-O-Glucoside on Intestinal Microbiota Dysbiosis and Drug Resistance Transmission Caused by Raoultella ornithinolytica B1645-1: Modulating the Composition of Intestinal Microbiota and Promoting the Transfer of blaNDM-1 Gene from Genus Enterococcus to Lactobacillus in Mice

open access: yesMicroorganisms, 2023
Raoultella ornithinolytica is an Enterobacteriaceae bacterium that can infect both humans and animals, while luteolin-7-O-glucoside (IOG) is a flavonoid that has broad effects on the intestinal microbiota of healthy animals. However, current studies lack
Zhaomeng Wu   +5 more
doaj   +1 more source

miRNA‐194 predicts favorable prognosis in gastric cancer and inhibits gastric cancer cell growth by targeting CCND1

open access: yesFEBS Open Bio, 2021
MicroRNAs (MiRNAs) play critical roles in regulating target gene expression and multiple cellular processes in human cancer malignant progression. However, the function of miR‐194 in gastric cancer (GC) remains unclear and controversial.
Jingjie Wang   +6 more
doaj   +1 more source

Embryonic Stem Cells in Cattle [PDF]

open access: yesReproduction in Domestic Animals, 2008
ContentsBecause of the potential use of embryonic stem cells (ESC), especially for genetic modifications, there is great interest in establishing domestic animals‐related ESCs. Unfortunately, despite considerable efforts, validated ESC lines in species other than mice and primates are yet to be isolated.
Munoz, M   +5 more
openaire   +5 more sources

Spatio-temporal model of Meox1 expression control involvement of Sca-1-positive stem cells in neointima formation through the synergistic effect of Rho/CDC42 and SDF-1α/CXCR4

open access: yesStem Cell Research & Therapy, 2021
Aims Neointimal hyperplasia remains a major obstacle in vascular regeneration. Sca-1-positive progenitor cells residing within the vascular adventitia play a crucial role in the assemblage of vascular smooth muscle cell (VSMC) and the formation of the ...
Yan Wu   +17 more
doaj   +1 more source

Qiliqiangxin reduced cardiomyocytes apotosis and improved heart function in infarcted heart through Pink1/Parkin -mediated mitochondrial autophagy

open access: yesBMC Complementary Medicine and Therapies, 2020
Background Qiliqiangxin (QLQX) is a preparation refined from a traditional Chinese medicine compound. It plays an important role in protecting cardiac function after myocardial infarction (MI). However, the underline mechanism of QLQX action is not clear.
Junyang Zhou   +14 more
doaj   +1 more source

Chicken embryonic stem cells as a non‐mammalian embryonic stem cell model [PDF]

open access: yesDevelopment, Growth & Differentiation, 2010
Embryonic stem cells (ESCs) were isolated in the early 1980s from mouse and in the late 1990s from primate and human. These cells present the unique property of self‐renewal and the ability to generate differentiated progeny in all embryonic lineages both in vitro and in vivo.
Lavial, Fabrice, Pain, Bertrand
openaire   +4 more sources

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