Comparative Analysis of Nuclear Transfer Embryo Derived Mouse Embryonic Stem Cells. Part I: Cellular characterization [PDF]
Embryonic stem cells derived from nuclear transfer embryos (ntESCs) are particularly valuable for regenerative medicine, as they are a patient-specific and histocompatible cell source for the treatment of varying diseases.
Julianna Kobolak +13 more
core +1 more source
ANGPTL8 is a negative regulator in pathological cardiac hypertrophy
Pathological cardiac hypertrophy is an independent risk factor for heart failure and is considered a target for the treatment of heart failure. However, the mechanisms underlying pathological cardiac hypertrophy remain largely unknown.
Lin Hu +12 more
doaj +1 more source
No association between myeloperoxidase gene rs2333227 G>A polymorphism and Alzheimer's disease risk: a meta-analysis and trial sequential analysis [PDF]
Evidence suggests that there is a close association between myeloperoxidase (MPO) gene rs2333227 G>A polymorphism with Alzheimer’s disease (AD) susceptibility.
Zhi-Cheng Fang +4 more
doaj +1 more source
Stem cells in the embryonic kidney [PDF]
The mammalian kidney, the metanephros, is formed by a reciprocally inductive interaction between two precursor tissues, the metanephric mesenchyme and the ureteric bud. The ureteric bud induces the metanephric mesenchyme to differentiate into the epithelia of glomeruli and renal tubules.
openaire +2 more sources
Nuclear FAM289-Galectin-1 interaction controls FAM289-mediated tumor promotion in malignant glioma
Background FAM92A1–289(abbreviated FAM289) is recognized as one of the newly-discovered putative oncogenes. However, its role and molecular mechanisms in promoting cancer progression has not yet been elucidated.
Xing Rong Guo +12 more
doaj +1 more source
Embryonic cortical neural stem cells migrate ventrally and persist as postnatal striatal stem cells [PDF]
Embryonic cortical neural stem cells apparently have a transient existence, as they do not persist in the adult cortex. We sought to determine the fate of embryonic cortical stem cells by following Emx1(IREScre); LacZ/EGFP double-transgenic murine cells ...
Seaberg, R.M. +18 more
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Hadassah, provider of 'Regulatory-Ready' pluripotent clinical-grade stem cell banks
The Hadassah hESC Research Center's aim is to be a supplier of clinical and research-grade human embryonic stem cell (hESC) lines. In 2012, we derived the first three entirely GMP-compliant and xeno-free, fully-characterised, feeder-dependent (human ...
Shelly E Tannenbaum +7 more
doaj +1 more source
The interplay between hepatocellular carcinoma (HCC) cells and the tumor microenvironment is essential for hepatocarcinogenesis, but their contributions to HCC development are incompletely understood.
Yujiu Gao +16 more
doaj +1 more source
Generation and characterization of erythroid cells from human embryonic stem cells and induced pluripotent stem cells : an overview [PDF]
Because of the imbalance in the supply and demand of red blood cells (RBCs), especially for alloimmunized patients or patients with rare blood phenotypes, extensive research has been done to generate therapeutic quantities of mature RBCs from ...
Bönig, Halvard-Björn +5 more
core +1 more source
Fresh or frozen? Classifying ‘spare' embryos for donation to human embryonic stem cell research [PDF]
This article is available open access, funded by the Wellcome Trust. It is distributed under a Creative Commons License (http://creativecommons.org/licenses/by/3.0/). Copyright @ 2010 Elsevier Ltd.United Kingdom (UK) funding to build human embryonic stem
Williams, C +11 more
core +1 more source

