Results 31 to 40 of about 65,698 (300)
eLife, 2022 Research and therapeutic applications using human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) require robust differentiation strategies. Efforts to improve hPSC-CM differentiation have largely overlooked the role of extracellular matrix (ECM).
Jianhua Zhang +9 more
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Inverse agonism of retinoic acid receptors directs epiblast cells into the paraxial mesoderm lineage
Stem Cell Research, 2018 We have investigated the differentiation of paraxial mesoderm from mouse embryonic stem cells utilizing a Tbx6-EYFP/Brachyury (T)-Cherry dual reporter system.
Ryan P. Russell +3 more
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Stem Cell Reports, 2017 Hematopoietic stem cells arise from mesoderm-derived hemogenic endothelium (HE) during embryogenesis in a process termed endothelial-hematopoietic transition (EHT).
Yang Li +6 more
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mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/nodal signaling in Xenopus ectodermal cells. [PDF]
PLoS ONE, 2012 BACKGROUND:In Xenopus early embryogenesis, various genes are involved with mesoderm formation. In particular, dorsal mesoderm contains the organizer region and induces neural tissues through the inhibition of bone morphogenetic protein (BMP) signaling ...
Aya Miyazaki +8 more
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New Insights Into Cranial Synchondrosis Development: A Mini Review
Frontiers in Cell and Developmental Biology, 2020 The synchondroses formed via endochondral ossification in the cranial base are an important growth center for the neurocranium. Abnormalities in the synchondroses affect cranial base elongation and the development of adjacent regions, including the ...
Noriko Funato, Noriko Funato
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The Origin of Mesoderm in Phoronids
Developmental Biology, 2002 Descriptive studies of phoronid development have concluded that the mesoderm of these animals originates from the endoderm during gastrulation. This interpretation has been tested by labeling one blastomere of 4- through 16-cell embryos and examining the position and germ layers occupied by the labeled clones of cells in the larva. No 2 injections gave
Freeman, Gary, Martindale, Mark Q.
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Rab7 is required for mesoderm patterning and gastrulation in Xenopus
Biology Open, 2021 Early embryogenesis requires tightly controlled temporal and spatial coordination of cellular behavior and signaling. Modulations are achieved at multiple levels, from cellular transcription to tissue-scale behavior.
Jennifer Kreis +2 more
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Early mesodermal phenotypes in splotch suggest a role for Pax3 in the formation of epithelial somites [PDF]
, 2001 The paired box containing transcription factor Pax3 is a crucial regulator of dermomyotome and muscle development. However, the allelic series of Pax3/Splotch mutants also displays characteristic vertebral column malformations, which do not result from ...
Schubert, Frank +17 more
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Early markers of induced pluripotent stem cell hematopoietic development
Медицинская иммунологияThe generation of immune cell populations from induced pluripotent stem cells (iPSCs) is a valuable model to study mechanisms that control hematopoietic development; it also is a promising approach to develop immunotherapeutic strategies to treat various
O. N. Sheveleva +2 more
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Frontiers in Neuroscience, 2023 Due to its long history, the study of human gross anatomy has not adequately incorporated modern embryological findings; consequently, the current understanding has often been incompatible with recent discoveries from molecular studies.
Shunsaku Homma +5 more
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