Results 31 to 40 of about 64,865 (357)

Cohesin Components Stag1 and Stag2 Differentially Influence Haematopoietic Mesoderm Development in Zebrafish Embryos

Frontiers in Cell and Developmental Biology, 2020
Cohesin is a multiprotein complex made up of core subunits Smc1, Smc3, and Rad21, and either Stag1 or Stag2. Normal haematopoietic development relies on crucial functions of cohesin in cell division and regulation of gene expression via three-dimensional
Sarada Ketharnathan, Anastasia Labudina, Julia A. Horsfield, Julia A. Horsfield   +3 more
doaj   +1 more source

Etv2/ER71 induces vascular mesoderm from Flk1+PDGFRα+ primitive mesoderm [PDF]

, 2011
Etv2 (Ets Variant 2) has been shown to be an indispensable gene for the development of hematopoietic cells (HPCs)/endothelial cells (ECs). However, how Etv2 specifies the mesoderm-generating HPCs/ECs remains incompletely understood.
Satomi Nishikawa, Misato Hayashi, Martin Lars Jakt, Shin-Ichi Nishikawa, Hiroshi Kataoka, Reiko Nakagawa, Naoki Izumi, Hiroshi Tarui, Yosuke Tanaka   +8 more
core   +1 more source

Homology of the cranial vault in birds: new insights based on embryonic fate-mapping and character analysis [PDF]

Royal Society Open Science, 2016
Bones of the cranial vault appear to be highly conserved among tetrapod vertebrates. Moreover, bones identified with the same name are assumed to be evolutionarily homologous. However, recent developmental studies reveal a key difference in the embryonic
Hillary C. Maddin, Nadine Piekarski, Elizabeth M. Sefton, James Hanken   +3 more
doaj   +1 more source

The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature [PDF]

, 2010
In vertebrates, body musculature originates from somites, whereas head muscles originate from the cranial mesoderm. Neck muscles are located in the transition between these regions.
Anthony Otto, Theis, S, Eldad Tzahor, Huang, R., Harel, Itamar, Qui, P, Shahragim Tajbakhsh, Valasek, Petr, Christ, B., Susanne Theis, Christ, Bodo, Ketan Patel, Pu, Q., Huang, R, Tajbakhsh, S., Ruijin Huang, Patel, Ketan, Tajbakhsh, S, Otto, Anthony, Pu, Qin, Tzahor, E, Harel, I., Petr Valasek, Harel, I, Itamar Harel, Christ, B, Bodo Christ, Theis, S., Tzahor, E., Huang, Ruijin, Qin Pu   +30 more
core   +1 more source

Early mesodermal phenotypes in splotch suggest a role for Pax3 in the formation of epithelial somites [PDF]

, 2001
The paired box containing transcription factor Pax3 is a crucial regulator of dermomyotome and muscle development. However, the allelic series of Pax3/Splotch mutants also displays characteristic vertebral column malformations, which do not result from ...
Schubert, Frank, Dietrich, Susanne, Schubert, F R, Kammandel, B, Lumsden, A, Mansouri, A, Tremblay, P., Tremblay, P, Schubert, F., Dietrich, S, Mansouri, A., Lumsden, A., Dietrich, S., Faisst, A., Gruss, P, Faisst, A M, Gruss, P., Kammandel, B.   +17 more
core   +1 more source

Cardiac differentiation of human pluripotent stem cells using defined extracellular matrix proteins reveals essential role of fibronectin

eLife, 2022
Research and therapeutic applications using human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) require robust differentiation strategies. Efforts to improve hPSC-CM differentiation have largely overlooked the role of extracellular matrix (ECM).
Jianhua Zhang, Zachery R Gregorich, Ran Tao, Gina C Kim, Pratik A Lalit, Juliana L Carvalho, Yogananda Markandeya, Deane F Mosher, Sean P Palecek, Timothy J Kamp   +9 more
doaj   +1 more source

Inverse agonism of retinoic acid receptors directs epiblast cells into the paraxial mesoderm lineage

Stem Cell Research, 2018
We have investigated the differentiation of paraxial mesoderm from mouse embryonic stem cells utilizing a Tbx6-EYFP/Brachyury (T)-Cherry dual reporter system.
Ryan P. Russell, Yu Fu, Yaling Liu, Peter Maye   +3 more
doaj   +1 more source

Repressor dimerization in the zebrafish somitogenesis clock [PDF]

, 2007
The oscillations of the somitogenesis clock are linked to the fundamental process of vertebrate embryo segmentation, yet little is known about their generation.
Olivier Cinquin, Cinquin, O
core   +1 more source

Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis

Stem Cell Reports, 2017
Hematopoietic stem cells arise from mesoderm-derived hemogenic endothelium (HE) during embryogenesis in a process termed endothelial-hematopoietic transition (EHT).
Yang Li, Patrick M. Brauer, Jastaranpreet Singh, Sintia Xhiku, Kogulan Yoganathan, Juan Carlos Zúñiga-Pflücker, Michele K. Anderson   +6 more
doaj   +1 more source

Evolutionarily conserved morphogenetic movements at the vertebrate head-trunk interface coordinate the transport and assembly of hypopharyngeal structures [PDF]

, 2014
International audienceThe vertebrate head-trunk interface (occipital region) has been heavily remodelled during evolution, and its development is still poorly understood.
Walters, Esther H, Lewis, AK, Dietrich, Susanne, El-Hanfy, Amira S., Gandesha, Saniel, Wotton, Karl R., Jorge, EC, Sharpe, Colin, Lawson, Jennifer A, Dietrich, S, Sobreira, Débora Rodrigues, Sharpe, C, Lewis, A. Kelsey, Kardon, Gabrielle, Lawson, JA, Lours-Calet, C, Jorge, Erika C., Alvares, Lucia Elvira, Sobreira, Debora R., Lawson, Jennifer A., Alvares, LE, Alvares, Lucia E, El-Hanfy, Amira S, Kelsey Lewis, A., Kelsey Lewis, A, Jorge, Erika C, Lours-Calet, Corinne, Sobreira, DR, Tada, M, Walters, EH, Alvares, Lucia E., Kardon, G, El-Hanfy, AS, Wotton, KR, Wotton, Karl R, Walters, Esther H., Tada, Masazumi, Gandesha, S   +37 more
core   +2 more sources