Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog +12 more
wiley +1 more source
Synchronous and symmetric migration of Drosophila caudal visceral mesoderm cells requires dual input by two FGF ligands [PDF]
Caudal visceral mesoderm (CVM) cells migrate synchronously towards the anterior of the Drosophila embryo as two distinct groups located on each side of the body, in order to specify longitudinal muscles that ensheath the gut.
Ghosh, Srimoyee +2 more
core +1 more source
New Insights Into Cranial Synchondrosis Development: A Mini Review
The synchondroses formed via endochondral ossification in the cranial base are an important growth center for the neurocranium. Abnormalities in the synchondroses affect cranial base elongation and the development of adjacent regions, including the ...
Noriko Funato, Noriko Funato
doaj +1 more source
Current perspectives of the signaling pathways directing neural crest induction. [PDF]
The neural crest is a migratory population of embryonic cells with a tremendous potential to differentiate and contribute to nearly every organ system in the adult body.
García-Castro, Martín I +1 more
core +2 more sources
Rab7 is required for mesoderm patterning and gastrulation in Xenopus
Early embryogenesis requires tightly controlled temporal and spatial coordination of cellular behavior and signaling. Modulations are achieved at multiple levels, from cellular transcription to tissue-scale behavior.
Jennifer Kreis +2 more
doaj +1 more source
Early markers of induced pluripotent stem cell hematopoietic development
The generation of immune cell populations from induced pluripotent stem cells (iPSCs) is a valuable model to study mechanisms that control hematopoietic development; it also is a promising approach to develop immunotherapeutic strategies to treat various
O. N. Sheveleva +2 more
doaj +1 more source
Due to its long history, the study of human gross anatomy has not adequately incorporated modern embryological findings; consequently, the current understanding has often been incompatible with recent discoveries from molecular studies.
Shunsaku Homma +5 more
doaj +1 more source
Gene expression analysis of bovine embryonic disc, trophoblast and parietal hypoblast at the start of gastrulation [PDF]
In cattle early gastrulation-stage embryos (Stage 5), four tissues can be discerned: (i) the top layer of the embryonic disc consisting of embryonic ectoderm (EmE); (ii) the bottom layer of the disc consisting of mesoderm, endoderm and visceral hypoblast
Berg, D +3 more
core +2 more sources
Adult-onset degeneration of adipose tissue in mice deficient for the Sox8 transcription factor
Although the transcription factor Sox8 is broadly expressed during embryogenesis in developing ectodermal and mesodermal tissues, mice develop surprisingly normally in the absence of Sox8.
Sabine I.E. Guth +3 more
doaj +1 more source
Complete Dorsal Pancreatic Agenesis and Unilateral Renal Agenesis: First Case Report and Review of Literature [PDF]
Dorsal pancreatic agenesis is very rare congenital anomaly of pancreas. Patients with this anomaly are usually asymptomatic or may present with abdominal pain or acute or chronic pancreatitis.
Manjit Motilal Bagul, Purva Traipathi
doaj +1 more source

