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The neural crest and neural crest defects [PDF]
Biomedical Reviews, 2002 The neural crest is a fascinating embryonic tissue for more than one reason. In the adult organism it gives rise to an array of distinct cell types and tissues. It is responsible for many birth defects, familial diseases and malignancies, and it is amenable to the elucidation of mechanisms that regulate stem cell differentiation.
Maya Sieber-Blum, Zhijian Zhang
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Genetics Underlying the Interactions between Neural Crest Cells and Eye Development
Journal of Developmental Biology, 2020 The neural crest is a unique, transient stem cell population that is critical for craniofacial and ocular development. Understanding the genetics underlying the steps of neural crest development is essential for gaining insight into the pathogenesis of ...
Jochen Weigele, Brenda L. Bohnsack
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Neural crest-derived mesenchymal cells require Wnt signaling for their development and drive invagination of the telencephalic midline. [PDF]
PLoS ONE, 2014 Embryonic neural crest cells contribute to the development of the craniofacial mesenchyme, forebrain meninges and perivascular cells. In this study, we investigated the function of ß-catenin signaling in neural crest cells abutting the dorsal forebrain ...
Youngshik Choe +2 more
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Cardiovascular Development and the Colonizing Cardiac Neural Crest Lineage
The Scientific World Journal, 2007 Although it is well established that transgenic manipulation of mammalian neural crest-related gene expression and microsurgical removal of premigratory chicken and Xenopus embryonic cardiac neural crest progenitors results in a wide spectrum of both ...
Paige Snider +3 more
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Frontiers in Cell and Developmental Biology, 2023 Neural crest-derived cells play essential roles in skin function and homeostasis. However, how they interact with environmental cues and differentiate into functional skin cells remains unclear.
Shize Ma +13 more
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Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration
eLife, 2020 During gastrulation, neural crest cells are specified at the neural plate border, as characterized by Pax7 expression. Using single-cell RNA sequencing coupled with high-resolution in situ hybridization to identify novel transcriptional regulators, we ...
Shashank Gandhi +5 more
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Cell Reports, 2023 Summary: Neural crest cells are multipotent cells that delaminate from the neuroepithelium, migrating throughout the embryo. Aberrant migration causes developmental defects.
Lisa Dobson +6 more
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Adipose stromal cells contain phenotypically distinct adipogenic progenitors derived from neural crest. [PDF]
PLoS ONE, 2013 Recent studies have shown that adipose-derived stromal/stem cells (ASCs) contain phenotypically and functionally heterogeneous subpopulations of cells, but their developmental origin and their relative differentiation potential remain elusive.
Yoshihiro Sowa +6 more
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Natural Sciences, 2022 The origin of the neurons and glia in the olfactory system of vertebrates has been controversial, with different cell types attributed to being of ectodermal placode versus neural crest lineage, depending upon the species.
Alison Koontz +2 more
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The heart of the neural crest: cardiac neural crest cells in development and regeneration [PDF]
Development, 2020 ABSTRACT Cardiac neural crest cells (cNCCs) are a migratory cell population that stem from the cranial portion of the neural tube. They undergo epithelial-to-mesenchymal transition and migrate through the developing embryo to give rise to portions of the outflow tract, the valves and the arteries of the heart.
Rajani M. George +2 more
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