Zebrafish arl6ip1 is required for neural crest development during embryogenesis.
PLoS ONE, 2012 BackgroundAlthough the embryonic expression pattern of ADP ribosylation factor-like 6 interacting protein 1 (Arl6ip1) has been reported, its function in neural crest development is unclear.Methods/principal findingsWe found that knockdown of Arl6ip1 ...
Chi-Tang Tu +3 more
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Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells [PDF]
, 2009 Stem cells, that is, cells that can both reproduce themselves and differentiate into functional cell types, attract much interest as potential aids to healing and disease therapy. Embryonic neural crest is pluripotent and generates the peripheral nervous
Negulyaev, YA +8 more
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Single-Cell Multiomic Approaches Reveal Diverse Labeling of the Nervous System by Common Cre-Drivers
Frontiers in Cellular Neuroscience, 2021 Neural crest development involves a series of dynamic, carefully coordinated events that result in human disease when not properly orchestrated. Cranial neural crest cells acquire unique multipotent developmental potential upon specification to generate ...
Rachel A. Keuls +7 more
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The “beginnings” of the neural crest
Developmental Biology, 2018 The neural crest has been the main object of my investigations during my career in science, up to now. It is a fascinating topic for an embryologist because of its two unique characteristics: its large degree of multipotency and the fact that its development involves a phase during which its component cells migrate all over the embryo and settle in ...
Le Douarin, Nicole, Dupin, Elisabeth
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The boundary cap: a source of neural crest stem cells that generate multiple sensory neuron subtypes [PDF]
, 2005 The boundary cap (BC) is a transient neural crest-derived group of cells located at the dorsal root entry zone (DREZ) that have been shown to differentiate into sensory neurons and glia in vivo.
Hjerling-Leffler, J +16 more
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PiacentinoLab/2021-Essential-function-and-targets-of-BMP-signaling-during-midbrain-neural-crest-delamination: DOI Release [PDF]
, 2023 Code and source data pertaining to Piacentino et al., 2021: Transcriptome profiling reveals BMP target genes during midbrain neural crest ...
Mike Piacentino
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FGF and retinoic acid activity gradients control the timing of neural crest cell emigration in the trunk [PDF]
, 2011 Coordination between functionally related adjacent tissues is essential during development. For example, formation of trunk neural crest cells (NCCs) is highly influenced by the adjacent mesoderm, but the molecular mechanism involved is not well ...
Quiroga, Alejandra C +23 more
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The role of the Zic genes in mouse neural crest development [PDF]
, 2004 The neural crest is an embryonic population of migratory, multipotent cells that are formed at the boundary of the neural and non-neural ectoderm around the time of neural tube closure.
Elms, Paul., Elms, Paul
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Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia [PDF]
, 2009 The peripheral nervous system (PNS) of higher vertebrates is segmented to align the spinal nerve roots with the vertebrae. This co-patterning is set up during embryogenesis, when vertebrae develop from the sclerotome layer of the metameric somites, and ...
Maden, CH +11 more
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Genetics Underlying the Interactions between Neural Crest Cells and Eye Development
Journal of Developmental Biology, 2020 The neural crest is a unique, transient stem cell population that is critical for craniofacial and ocular development. Understanding the genetics underlying the steps of neural crest development is essential for gaining insight into the pathogenesis of ...
Jochen Weigele, Brenda L. Bohnsack
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