Results 21 to 30 of about 132,267 (353)
Cranial Neural Crest Explants [PDF]
Cold Spring Harbor Protocols, 2018 The cranial neural crest (CNC) explant assay was originally designed to assess the basic requirements for CNC migration in vitro. This protocol describes the key parameters of CNC explants in Xenopus laevis, with a focus on how to extirpate CNC cells and assay their migration in vitro.
Hélène, Cousin, Dominique, Alfandari
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Zebrafish arl6ip1 is required for neural crest development during embryogenesis.
PLoS ONE, 2012 BackgroundAlthough the embryonic expression pattern of ADP ribosylation factor-like 6 interacting protein 1 (Arl6ip1) has been reported, its function in neural crest development is unclear.Methods/principal findingsWe found that knockdown of Arl6ip1 ...
Chi-Tang Tu +3 more
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Single-Cell Multiomic Approaches Reveal Diverse Labeling of the Nervous System by Common Cre-Drivers
Frontiers in Cellular Neuroscience, 2021 Neural crest development involves a series of dynamic, carefully coordinated events that result in human disease when not properly orchestrated. Cranial neural crest cells acquire unique multipotent developmental potential upon specification to generate ...
Rachel A. Keuls +7 more
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Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signaling [PDF]
, 2006 In vertebrate embryos, neural crest cells migrate only through the anterior half of each somite while avoiding the posterior half. We demonstrate that neural crest cells express the receptor neuropilin 2 (Npn2), while its repulsive ligand semaphorin 3F ...
Bronner-Fraser, Marianne +3 more
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Cell, 2010 The neural crest is a transient population of cells that emerges from the neural tube during the early stages of embryonic development. Neural crest cells are unique to vertebrates and have properties similar to stem cells, including the ability to differentiate into many cell types (i.e., multipotency) and to regenerate.
Sauka-Spengler, T, Bronner, M
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Molecular mechanisms of neural crest formation [PDF]
, 1999 The neural crest is a transient population of multipotent precursor cells named for its site of origin at the crest of the closing neural folds in vertebrate embryos.
Bronner-Fraser, Marianne +1 more
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The neural crest and neural crest defects
Biomedical Reviews, 2002 The neural crest is a fascinating embryonic tissue for more than one reason. In the adult organism it gives rise to an array of distinct cell types and tissues. It is responsible for many birth defects, familial diseases and malignancies, and it is amenable to the elucidation of mechanisms that regulate stem cell differentiation.
Maya Sieber-Blum, Zhijian Zhang
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Characterization of Pax3 and Sox10 Transgenic Xenopus Laevis Embryos as Tools to Study Neural Crest Development [PDF]
, 2018 The neural crest is a multipotent population of cells that originates a variety of cell types. Many animal models are used to study neural crest induction, migration and differentiation, with amphibians and birds being the most widely used systems.
Alkobtawi, Mansour +7 more
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Genetics Underlying the Interactions between Neural Crest Cells and Eye Development
Journal of Developmental Biology, 2020 The neural crest is a unique, transient stem cell population that is critical for craniofacial and ocular development. Understanding the genetics underlying the steps of neural crest development is essential for gaining insight into the pathogenesis of ...
Jochen Weigele, Brenda L. Bohnsack
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Neural crest-derived mesenchymal cells require Wnt signaling for their development and drive invagination of the telencephalic midline. [PDF]
PLoS ONE, 2014 Embryonic neural crest cells contribute to the development of the craniofacial mesenchyme, forebrain meninges and perivascular cells. In this study, we investigated the function of ß-catenin signaling in neural crest cells abutting the dorsal forebrain ...
Youngshik Choe +2 more
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