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Knockdown of klotho Leads to Cell Movement Impairment during Zebrafish Gastrulation
Fishes, 2023 (1) Background: Klotho is a multifunctional protein, but its biophysiological roles during fish early development are unclear. (2) Methods: We carried out anti-sense Klotho morpholino injection and whole-mount in situ hybridization experiments in this ...
Heng-Chih Pan +6 more
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Local cell interactions and self-amplifying individual cell ingression drive amniote gastrulation
eLife, 2014 Gastrulation generates three layers of cells (ectoderm, mesoderm, endoderm) from a single sheet, while large scale cell movements occur across the entire embryo.
Octavian Voiculescu +3 more
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The Birth of the Eye Vesicle: When Fate Decision Equals Morphogenesis
Frontiers in Neuroscience, 2018 As the embryonic ectoderm is induced to form the neural plate, cells inside this epithelium acquire restricted identities that will dictate their behavior and progressive differentiation.
Florence A. Giger, Corinne Houart
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MicroRNA-16 inhibits cell proliferation and migration by targeting heat shock protein 70 in heat-denatured dermal fibroblasts [PDF]
The Korean Journal of Internal Medicine, 2019 Background/Aims This study aimed to investigate the precise mechanism and function of miR-16 in heat-denatured primary human dermal fibroblasts. Methods Primary human dermal fibroblasts were separated from normal human skin samples.
Chun Zhang +4 more
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Cell Adhesion & Migration, 2019 The most prominent cancer-associated fibroblasts (CAFs) in tumor stroma is known to form a protective structure to support tumor growth. Anterior gradient-2 (AGR2), a tumor secretory protein is believed to play a pivotal role during tumor ...
Hitesh Bhagavanbhai Mangukiya +7 more
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Inhibition of colorectal cancer cell proliferation, invasion, and migration, and induction of epithelial-mesenchymal transition via TFF1 silencing [PDF]
Vojnosanitetski PregledBackground/Aim. The identification of aberrant genes associated with colorectal cancer (CRC) and understanding their pathogenic mechanisms are important for early diagnosis and the determination of appropriate therapy.
Zhao Jing +7 more
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Frontiers in Bioengineering and Biotechnology, 2022 The lack of bioactivity in three-dimensional (3D)-printing of poly-є-caprolactone (PCL) scaffolds limits cell-material interactions in bone tissue engineering.
Sonia Abbasi-Ravasjani +7 more
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Molecules, 2021 Current cell-based bone tissue regeneration strategies cannot cover large bone defects. K-carrageenan is a highly hydrophilic and biocompatible seaweed-derived sulfated polysaccharide, that has been proposed as a promising candidate for tissue ...
Wei Cao +12 more
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Leptin affects filopodia and cofilin in NK-92 cells in a dose- and time-dependent manner
European Journal of Histochemistry, 2018 Hyperleptinemia, associated with obesity, is related with immune dysfunction and carcinogenesis. Natural Killer (NK) cells, a major component of the innate immune system are mediators of anti-tumor immunity and the most actively migrating cells among ...
Jana Oswald +5 more
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Effect of protein kinase N1 on the biological behavior of human glioma
Chinese Journal of Contemporary Neurology and Neurosurgery, 2020 Objective To study the expression of protein kinase N1 (PKN1) in glioma and its influence on the biological behavior of glioma cells. Methods The expression of PKN1 gene was verified via GEPIA database, and LN229, U87 and A172 gliomas cells were detected
Yu⁃bing HAO +5 more
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