Integrative transcriptomic analysis in human and mouse model of anaphylaxis identifies gene signatures associated with cell movement, migration and neuroinflammatory signalling [PDF]
Frontiers in Immunology, 2022 BackgroundAnaphylaxis is an acute life-threatening allergic reaction and a concern at a global level; therefore, further progress in understanding the underlying mechanisms and more effective strategies for diagnosis, prevention and management are needed.
Matija Rijavec +14 more
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ATP levels influence cell movement during the mound phase in Dictyostelium discoideum as revealed by ATP visualization and simulation [PDF]
FEBS Open Bio, 2022 Cell migration plays an important role in multicellular organism development. The cellular slime mold Dictyostelium discoideum is a useful model organism for the study of cell migration during development.
Haruka Hiraoka +6 more
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Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle–mediated release of ezrin to inhibit tumour cell movement [PDF]
Journal of Extracellular Vesicles, 2020 Tumour metastasis suppressor KAI1/CD82 inhibits tumour cell movement. As a transmembrane protein, tetraspanin CD82 bridges the interactions between membrane microdomains of lipid rafts and tetraspanin-enriched microdomains (TEMs). In this study, we found
Chao Huang +4 more
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The use of animal models in rheumatoid arthritis research [PDF]
Journal of Yeungnam Medical Science, 2023 The pathological hallmark of rheumatoid arthritis (RA) is a synovial pannus that comprises proliferating and invasive fibroblast-like synoviocytes, infiltrating inflammatory cells, and an associated neoangiogenic response.
Jin-Sun Kong +2 more
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DBNLS232 regulates formation of filopodia and promotes cell migration in A549 cells
陆军军医大学学报, 2023 Objective To investigate the role of site-specific phosphorylation of adaptor protein Drebrin-like (DBNL) in regulating the formation of filopodia and the migration and movement of lung cancer A549 cells.
YIN Xun, YIN Xun, ZHANG Tao, ZHANG Tao
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Integrated analysis of cell shape and movement in moving frame
Biology Open, 2021 The cell's movement and morphological change are two interrelated cellular processes. An integrated analysis is needed to explore the relationship between them. However, it has been challenging to investigate them as a whole. The cell's trajectory can be
Yusri Dwi Heryanto +5 more
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Frontiers in Cell and Developmental Biology, 2021 Adhesion of basal keratinocytes to the underlying extracellular matrix (ECM) plays a key role in the control of skin homeostasis and response to injury.
Willow Hight-Warburton +8 more
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Transcriptional Changes in CD16+ Monocytes May Contribute to the Pathogenesis of COVID-19
Frontiers in Immunology, 2021 The COVID-19 pandemic has caused more than three million deaths globally. The severity of the disease is characterized, in part, by a dysregulated immune response.
Vanessa Chilunda +10 more
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Chinese Journal of Contemporary Neurology and Neurosurgery, 2022 Objective To investigate the effects of JSH⁃23 combined with Stattic targeting inhibition of nuclear factor⁃κB (NF⁃κB) and signal transducer and activator of transcription factor 3 (STAT3) signaling pathways on the proliferation and migration ability of ...
REN Xiao +9 more
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Knockdown of klotho Leads to Cell Movement Impairment during Zebrafish Gastrulation
Fishes, 2023 (1) Background: Klotho is a multifunctional protein, but its biophysiological roles during fish early development are unclear. (2) Methods: We carried out anti-sense Klotho morpholino injection and whole-mount in situ hybridization experiments in this ...
Heng-Chih Pan +6 more
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