Matrix metalloproteinases in the process of invasion and metastasis of breast cancer [PDF]
Metastatic cascade in malignant tumors, including breast cancer, starts with localized invasion of the host tissue. This process, requiring that tumor cells separate from each other, includes loss of homotypic and heterotypic cell adhesion and cell-cell ...
Konjević Gordana, Stanković Sandra
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Mammaglobin expression in tissue as a predictor of breast carcinoma aggressiveness [PDF]
Background/Aim. Human mammaglobin is considered to be one of the most significant markers of hematogenous dissemination of breast carcinoma. This paper aimed to indicate the important role of peritumoral tissue as an active participant in the ...
Milošević Bojan +8 more
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Healthy Male Individuals Possess Higher Plasma HER-2 Level than Females [PDF]
Considering HER2 as one of the well-known biomarkers in the cancer field, and published articles regarding serumlevels of HER2, in this paper we tried to highlight the issue that most studies don’t stratify the HER-2 concentrationof individuals in terms ...
Sepand Tehrani Fateh +8 more
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Tumor budding in tumor tissue among operatively treated patients with lung adenocarcinoma [PDF]
Background/Aim. The histological phenomenon of tumor budding is being recognized as an important determinant of disease progression and poor prognosis in various types of carcinoma.
Vasilijević Milena +2 more
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Endometrial carcinoma is one of the most frequent gynecological cancers in developed countries. Lymphovascular space invasion (LVSI), histological grade, and myometrial invasion (MMI) are important prognostic factors of endometrial carcinoma.
Azita Rafiee, Fereshteh Mohammadizadeh
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Down-regulation of transient receptor potential melastatin member 7 prevents migration and invasion of renal cell carcinoma cells via inactivation of the Src and Akt pathway [PDF]
Purpose: Transient receptor potential melastatin member 7 (TRPM7), an ion channel and serine/threonine protein kinase, has been linked with distinct human malignancies.
Yun-Sok Ha +8 more
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Is the oncological impact of vascular invasion more important in right colon cancer?
Vascular invasion is an unfavorable prognostic factor for the recurrence and systemic metastasis of colon cancer. An interesting study in this issue evaluate the difference in the oncological impact of vascular invasion according to tumor side in colon ...
Gyung Mo Son
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N-glycosylation in non-invasive and invasive intraductal papillary mucinous neoplasm
AbstractIntraductal papillary mucinous neoplasms (IPMNs), often found incidentally, are potentially malignant cystic tumors of the pancreas. Due to the precancerous nature, IPMNs lacking malignant features should be kept on surveillance. The follow-up relies on magnetic resonance imaging, which has a limited accuracy to define the high-risk patients ...
Heini Nieminen +10 more
openaire +4 more sources
FSP-1 expression in cancer cells is relevant to long-term oncological outcomes in nonmetastatic colorectal cancer [PDF]
Purpose Recent studies have revealed that the expression of cancer-associated fibroblast (CAF) activation biomarkers in cancer cells is associated with clinical outcomes in patients with certain types of malignant tumors.
Sun Bin Im +6 more
doaj +1 more source
Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade [PDF]
Gelsolin is a cytoskeletal protein which participates in actin filament dynamics and promotes cell motility and plasticity. Although initially regarded as a tumor suppressor, gelsolin expression in certain tumors correlates with poor prognosis and ...
Alan Prem Kumar +14 more
core +10 more sources

