Results 41 to 50 of about 93,862 (267)

Specific features of proliferation and apoptosis in non-invasive adenocarcinoma of endometrium and adenocarcinoma with invasion into myometrium

Patologìâ, 2014
Introduction. The development of tumors occurs as a multistage process, where each step corresponds to certain genetic changes of cells and it is a reflection characteristic of different histological forms of cancer. This usually multiple changes include
V. O. Tumanskiy, M. M. Baudarbekova, O. V. Chepets   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pathological and Clinical Significance of Tumor Budding and Its Association with Epithelial-Mesenchymal Transition in Colorectal Carcinoma: A Retrospective Observational Study [PDF]

Iranian Journal of Medical Sciences
Background: Metastases, not the primary tumor, account for most cancer-related deaths. Tumor budding, thought to represent epithelial-mesenchymal transition (EMT), has garnered attention due to its association with invasion and migration. This study aims
Bashar Al Hassawi
doaj   +1 more source

Research Progress of Long Non-Coding RNA GAS5 in Malignant Tumors

Frontiers in Oncology, 2022
With completing the whole genome sequencing project, awareness of lncRNA further deepened. The growth arrest-specific transcript 5 (GAS5) was initially identified in growth-inhibiting cells.
Guohong Lin, Tianzhun Wu, Xing Gao, Ziqin He, Wenwei Nong   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Significance of color doppler ultrasonography in the assessment of pancreatic carcinoma vascular invasion [PDF]

Vojnosanitetski Pregled, 2006
Background/Aim. It is highly appreciated to provide exact data on vascular invasion of pancreatic carcinoma relying as much as possible on non-invasive diagnostic procedures.
Alempijević Tamara, Kovačević Nada, Tomić Dragan, Đuranović Srđan, Krstić Miodrag   +4 more
doaj   +1 more source

Ginseng-based carbon dots inhibit the growth of squamous cancer cells by increasing ferroptosis

Frontiers in Oncology, 2023
BackgroundRecent studies indicated that Ginseng potentiate cancer treatments. Ginseng-based carbon dots (GCDs) might possess properties to kill cancer cells and inhibit malignant tumor development and invasion.
Zilin Wang, Zilin Wang, Jing Han, Jing Han, Zhiyong Guo, Zhiyong Guo, Zhiyong Guo, Hao Wu, Hao Wu, Hao Wu, Yige Liu, Yige Liu, Yige Liu, Wenying Wang, Chenping Zhang, Chenping Zhang, Jiannan Liu, Jiannan Liu   +17 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

CT-based intratumoral and peritumoral radiomics nomogram to predict spread through air spaces in lung adenocarcinoma with diameter ≤ 3 cm: A multicenter study

European Journal of Radiology Open
Purpose: The aim of this study was to explore and develop a preoperative and noninvasive model for predicting spread through air spaces (STAS) status in lung adenocarcinoma (LUAD) with diameter ≤ 3 cm.
Yangfan Su, Junli Tao, Xiaosong Lan, Changyu Liang, Xuemei Huang, Jiuquan Zhang, Kai Li, Lihua Chen   +7 more
doaj   +1 more source