Results 61 to 70 of about 99,952 (361)

Conflicting or complementary role of computed tomography (CT) and positron emission tomography (PET)/CT in the assessment of thymic cancer and thymoma: Our experience and literature review [PDF]

, 2015
Background: To evaluate the role of computed tomography (CT) and positron emission tomography (PET)/CT in patients with thymic cancer and thymoma at initial staging.
Calabrese, Fiorella, Evangelista, Laura, Nannini, Nazarena, Panunzio, Annalori, Polverosi, Roberta, Pomerri, Fabio, Scagliori, Elena   +6 more
core   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

CT-based intratumoral and peritumoral radiomics nomogram to predict spread through air spaces in lung adenocarcinoma with diameter ≤ 3 cm: A multicenter study

European Journal of Radiology Open
Purpose: The aim of this study was to explore and develop a preoperative and noninvasive model for predicting spread through air spaces (STAS) status in lung adenocarcinoma (LUAD) with diameter ≤ 3 cm.
Yangfan Su, Junli Tao, Xiaosong Lan, Changyu Liang, Xuemei Huang, Jiuquan Zhang, Kai Li, Lihua Chen   +7 more
doaj   +1 more source

Pathological and Clinical Significance of Tumor Budding and Its Association with Epithelial-Mesenchymal Transition in Colorectal Carcinoma: A Retrospective Observational Study [PDF]

Iranian Journal of Medical Sciences
Background: Metastases, not the primary tumor, account for most cancer-related deaths. Tumor budding, thought to represent epithelial-mesenchymal transition (EMT), has garnered attention due to its association with invasion and migration. This study aims
Bashar Al Hassawi
doaj   +1 more source

Minimally invasive differential diagnosis of melanocytic intraocular neoplasms

Russian Ophthalmological Journal, 2023
Purpose: to analyze the mutation frequency of the GNAQ/GNA11 gene in circulating tumor DNA and genotypes of the polymorphic marker C3435T of the ABCB1 gene in a large sample of patients with intraocular melanocytic neoplasms (IMN).Material and methods.
A. Yu. Tsygankov, S. V. Saakyan, E. B. Myakoshina, A. M. Burdennyi, V. I. Loginov   +4 more
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

RAB family gene expression in breast cancer cells under influence of paclitaxel [PDF]

, 2011
The aim of this study was to investigate the role of paclitaxel on RAB family of genes in primary breast cancer cell lines. The cancer breast cells obtained from 40 women during mastectomy were used to address this issue. The group included patients with
Andrzej Wilkolaski, Jolanta Rzymowska, Piotr Maj, Tadeusz Malewski   +3 more
core   +1 more source

Molecular Genetics of Intracranial Meningiomas with Emphasis on Canonical Wnt Signalling. [PDF]

, 2016
Research over the last decade recognized the importance of novel molecular pathways in pathogenesis of intracranial meningiomas. In this review, we focus on human brain tumours meningiomas and the involvement of Wnt signalling pathway genes and proteins ...
Kafka, Anja, Lechpammer, Mirna, Pećina-Šlaus, Nives   +2 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

INVASIVE CARCINOMA DERIVED FROM INTRADUCTAL PAPILLARY NEOPLASM

Pancreas, 2007
膵管内乳頭粘液性腫瘍（intraductal papillary-mucinous neoplasms：IPMNs）は，1982年大橋らが主膵管内の多量の粘液貯留に起因する主膵管拡張と十二指腸乳頭口開大などの臨床的特徴を示す予後の良い膵癌として「粘液産生膵癌」と命名し報告して以来，四半世紀の25年が経過した．四半世紀過ぎたことにより"IPMNs由来の浸潤癌"も多く報告がなされており，これらの報告をもとに特徴をまとめると以下のようになる．平均年齢は65歳前後，性差は男性に多い．好発部位は頭部で，60%以上同部がしめる．浸潤部の組織型はほとんど（90%以上）が粘液癌と管状腺癌である．両者の比率はほぼ同様であり，通常の浸潤性膵管癌組織型における粘液癌のしめる頻度から考えると粘液癌の比率が非常に高い ...
openaire   +2 more sources