A proteomic approach to identify endosomal cargoes controlling cancer invasiveness [PDF]
, 2017 We have previously shown that Rab17 - a small GTPase associated with epithelial polarity - is specifically suppressed by ERK2 signalling to promote an invasive phenotype.
Diaz-Vera, Jesica +8 more
core +2 more sources
Multiparametric MRI of the bladder: inter-observer agreement and accuracy with the Vesical Imaging-Reporting and Data System (VI-RADS) at a single reference center [PDF]
, 2019 Objectives: To evaluate accuracy and inter-observer variability using Vesical Imaging-Reporting and Data System (VI-RADS) for discrimination between non-muscle invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC).
Barchetti, Giovanni +11 more
core +1 more source
Uterine Rupture Due to Invasive Metastatic Gestational Trophoblastic Neoplasm [PDF]
Western Journal of Emergency Medicine, 2013 While complete molar pregnancies are rare, they are wrought with a host of potential complications to include invasive gestational trophoblastic neoplasia. Persistent gestational trophoblastic disease following molar pregnancy is a potentially fatal complication that must be recognized early and treated aggressively for both immediate and long-term ...
Bruner, David I +2 more
openaire +5 more sources
Invasive mucinous cystic neoplasms of the pancreas
Experimental and Molecular Pathology, 2012 Mucinous cystic neoplasms (MCN) and intraductal papillary mucinous neoplasms (IPMN) of the pancreas both appear to have been included and intermixed in some early reports of pancreatic cystic neoplasms. Recognition of their distinguishing features evolved during the last decade of the twentieth century.
Baker, Ml +7 more
openaire +2 more sources
Role of hypoxia-related proteins in adenoid cystic carcinoma invasion
Diagnostic Pathology, 2020 Background Among cancers affecting the oral cavity, adenoid cystic carcinoma (ACC) is a relatively common malignant neoplasm. It has high rates of metastasis and recurrence and is associated with significant morbidity.
Raíssa Pinheiro de Mendonça +9 more
doaj +1 more source
Parameters of Stromal Activation and Epithelial to Mesenchymal Transition as Predictive Biomarkers for Induction Chemotherapy in Patients With Locally Advanced Oral Cavity and Oropharyngeal Squamous Cell Cancer [PDF]
Clinical and Experimental Otorhinolaryngology, 2016 Objectives Induction chemotherapy (IC) is likely to be effective for biologically distinct subgroups of oral cancer and biomarker development may lead to identification of those patients.
Jana Geweiler +3 more
doaj +1 more source
Ontology-Based MEDLINE Document Classification [PDF]
, 2007 An increasing and overwhelming amount of biomedical information is available in the research literature mainly in the form of free-text. Biologists need tools that automate their information search and deal with the high volume and ambiguity of free-text.
J.T. Eppig +4 more
core +2 more sources
Frontiers in Oncology, 2022 ObjectiveTo investigate whether radiomics can help radiologists and thoracic surgeons accurately predict invasive adenocarcinoma (IAC) manifesting as part-solid nodules (PSNs) with solid components <6 mm and provide a basis for rational clinical ...
Teng Zhang +8 more
doaj +1 more source
Keratocystic odontogenic tumor overexpresses invadopodia-related proteins, suggesting invadopodia formation [PDF]
, 2016 OBJECTIVE: Keratocystic odontogenic tumor (KOT) is an odontogenic neoplasm that shows aggressive clinical behavior and local invasiveness. Invadopodia are actin-rich cellular protrusions exhibiting proteolytic pericellular activity, thereby inducing ...
Brasil da Silva, W +8 more
core +1 more source
Cancer Imaging, 2019 Objectives To explore the feasibility of diagnosing microvascular invasion (MVI) with radiomics, to compare the diagnostic performance of different models established by each method, and to determine the best diagnostic model based on radiomics.
Ming Ni +10 more
doaj +1 more source