Integrative transcriptomic analysis in human and mouse model of anaphylaxis identifies gene signatures associated with cell movement, migration and neuroinflammatory signalling [PDF]
BackgroundAnaphylaxis is an acute life-threatening allergic reaction and a concern at a global level; therefore, further progress in understanding the underlying mechanisms and more effective strategies for diagnosis, prevention and management are needed.
Matija Rijavec +14 more
doaj +2 more sources
ATP levels influence cell movement during the mound phase in Dictyostelium discoideum as revealed by ATP visualization and simulation [PDF]
Cell migration plays an important role in multicellular organism development. The cellular slime mold Dictyostelium discoideum is a useful model organism for the study of cell migration during development.
Haruka Hiraoka +6 more
doaj +2 more sources
The use of animal models in rheumatoid arthritis research [PDF]
The pathological hallmark of rheumatoid arthritis (RA) is a synovial pannus that comprises proliferating and invasive fibroblast-like synoviocytes, infiltrating inflammatory cells, and an associated neoangiogenic response.
Jin-Sun Kong +2 more
doaj +1 more source
DBNLS232 regulates formation of filopodia and promotes cell migration in A549 cells
Objective To investigate the role of site-specific phosphorylation of adaptor protein Drebrin-like (DBNL) in regulating the formation of filopodia and the migration and movement of lung cancer A549 cells.
YIN Xun, YIN Xun, ZHANG Tao, ZHANG Tao
doaj +1 more source
Integrated analysis of cell shape and movement in moving frame
The cell's movement and morphological change are two interrelated cellular processes. An integrated analysis is needed to explore the relationship between them. However, it has been challenging to investigate them as a whole. The cell's trajectory can be
Yusri Dwi Heryanto +5 more
doaj +1 more source
Adhesion of basal keratinocytes to the underlying extracellular matrix (ECM) plays a key role in the control of skin homeostasis and response to injury.
Willow Hight-Warburton +8 more
doaj +1 more source
Transcriptional Changes in CD16+ Monocytes May Contribute to the Pathogenesis of COVID-19
The COVID-19 pandemic has caused more than three million deaths globally. The severity of the disease is characterized, in part, by a dysregulated immune response.
Vanessa Chilunda +10 more
doaj +1 more source
Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour [PDF]
The mechanism of eukaryotic chemotaxis remains unclear despite intensive study. The most frequently described mechanism acts through attractants causing actin polymerization, in turn leading to pseudopod formation and cell movement.
Peter J M van Haastert +20 more
core +4 more sources
Objective To investigate the effects of JSH⁃23 combined with Stattic targeting inhibition of nuclear factor⁃κB (NF⁃κB) and signal transducer and activator of transcription factor 3 (STAT3) signaling pathways on the proliferation and migration ability of ...
REN Xiao +9 more
doaj +1 more source
Non-cell-autonomous small RNA silencing in Arabidopsis female gametes. [PDF]
In recent years, small RNA movement has been both hypothesized and shown to be an integral part of the epigenetic DNA methylation reprogramming occurring during plant reproduction.1It was suggested that the release of epigenetic silencing in accessory ...
Schröder, Jens A +2 more
core +1 more source

