Results 31 to 40 of about 1,616,474 (251)
Mapping the Response of Human Osteocytes in Native Matrix to Mechanical Loading Using RNA Sequencing
JBMR Plus, 2023 Osteocytes sense mechanical loads and transduce mechanical signals into a chemical response. They are the most abundant bone cells deeply embedded in mineralized bone matrix, which affects their regulatory activity in the mechanical adaptation of bone ...
Chen Zhang +6 more
doaj +1 more source
Frontiers in Bioinformatics, 2022 Malaria is a disease caused by Plasmodium parasites, resulting in over 200 million infections and 400,000 deaths every year. A critical step of malaria infection is when sporozoites, injected by mosquitoes, travel to the liver and form liver stages ...
Viktor S. Zenkov +5 more
doaj +1 more source
Emergence of collective propulsion through cell-cell adhesion
, 2017 The mechanisms driving the collective movement of cells remain poorly understood. To contribute toward resolving this mystery, a model was formulated to theoretically explore the possible functions of polarized cell-cell adhesion in collective cell ...
Matsushita, Katsuyoshi
core +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Bioactive coatings are promising for improving osseointegration and the long-term success of titanium dental or orthopaedic implants. Biomimetic octacalcium phosphate (OCP) coating can be used as a carrier for osteoinductive agents.
Wei Cao +9 more
doaj +1 more source
A framework for quantification and physical modeling of cell mixing applied to oscillator synchronization in vertebrate somitogenesis [PDF]
, 2017 In development and disease, cells move as they exchange signals. One example is found in vertebrate development, during which the timing of segment formation is set by a ‘segmentation clock’, in which oscillating gene expression is synchronized across a ...
Bhavna, Rajasekaran +3 more
core +4 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Models for pattern formation in somitogenesis: a marriage of cellular and molecular biology [PDF]
, 2002 Somitogenesis, the process by which a bilaterally symmetric pattern of cell aggregations is laid down in a cranio-caudal sequence in early vertebrate development, provides an excellent model study for the coupling of interactions at the molecular and ...
Gavaghan, D. J. +4 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Coordinated Morphogenetic Mechanisms Shape the Vertebrate Eye
Frontiers in Neuroscience, 2017 The molecular bases of vertebrate eye formation have been extensively investigated during the past 20 years. This has resulted in the definition of the backbone of the gene regulatory networks controlling the different steps of eye development and has ...
Juan-Ramon Martinez-Morales +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman +8 more
wiley +1 more source