Inhibition of colorectal cancer cell proliferation, invasion, and migration, and induction of epithelial-mesenchymal transition via TFF1 silencing [PDF]
Background/Aim. The identification of aberrant genes associated with colorectal cancer (CRC) and understanding their pathogenic mechanisms are important for early diagnosis and the determination of appropriate therapy.
Zhao Jing +7 more
doaj +1 more source
Importin-α-mediated nucleolar localization of potato mop-top virus TRIPLE GENE BLOCK1 (TGB1) protein facilitates virus systemic movement, whereas TGB1 self-interaction is required for cell-to-cell movement in Nicotiana benthamiana [PDF]
This work was supported by the Swedish Research Council Formas (to E.I.S.), the Carl Tryggers Foundation (to E.I.S. and N.I.L.), the Swedish Institute (to N.I.L.), and the Rural and Environmental Science and Analytical Services Division strategic ...
Savenkov, Eugene I. +5 more
core +1 more source
Cell Migration with Multiple Pseudopodia: Temporal and Spatial Sensing Models [PDF]
Cell migration triggered by pseudopodia (or “false feet”) is the most used method of locomotion. A 3D finite element model of a cell migrating over a 2D substrate is proposed, with a particular focus on the mechanical aspects of the biological phenomenon.
ALLENA, Rachele
core +1 more source
Leptin affects filopodia and cofilin in NK-92 cells in a dose- and time-dependent manner
Hyperleptinemia, associated with obesity, is related with immune dysfunction and carcinogenesis. Natural Killer (NK) cells, a major component of the innate immune system are mediators of anti-tumor immunity and the most actively migrating cells among ...
Jana Oswald +5 more
doaj +1 more source
Modeling cell movement in anisotropic and heterogeneous network tissues [PDF]
Cell motion and interaction with the extracellular matrix is studied deriving a kinetic model and considering its diffusive limit. The model takes into account of chemotactic and haptotactic effects, and obtains friction as a result of the interactions ...
A. Chauviere +6 more
core +1 more source
The lack of bioactivity in three-dimensional (3D)-printing of poly-є-caprolactone (PCL) scaffolds limits cell-material interactions in bone tissue engineering.
Sonia Abbasi-Ravasjani +7 more
doaj +1 more source
Gap junctions modulate interkinetic nuclear movement in retinal progenitor cells [PDF]
During early retinal development, progenitor cells must divide repeatedly to expand the progenitor pool. During G1 and G2 of the cell cycle, progenitor cell nuclei migrate back-and-forth across the proliferative zone in a process termed interkinetic ...
Lüneborg, N.L. +7 more
core +1 more source
OBJECTIVE Hepatocyte growth factor (HGF) expression is closely related to the progression and poor prognosis of colorectal cancer patients. In this study, we investigated the effects on proliferation and migration of the human colon carcinoma cell line ...
Wei GUO +6 more
doaj +1 more source
Current cell-based bone tissue regeneration strategies cannot cover large bone defects. K-carrageenan is a highly hydrophilic and biocompatible seaweed-derived sulfated polysaccharide, that has been proposed as a promising candidate for tissue ...
Wei Cao +12 more
doaj +1 more source
SUMO wrestling in cell movement [PDF]
Small ubiquitin-like modifier (SUMO) proteins 1, 2 and 3 can be covalently conjugated to specific lysine residues on target proteins in a process dubbed SUMOylation. This conserved posttranslational modification that was reported for the first time in 1996 has emerged as an important regulatory mechanism in cell physiology, especially in nuclear ...
Miia M, Rytinki, Jorma J, Palvimo
openaire +2 more sources

