Modelling cell movement and chemotaxis pseudopod based feedback [PDF]
, 2011 A computational framework is presented for the simulation of eukaryotic cell migration and chemotaxis. An empirical pattern formation model, based on a system of non-linear reaction-diffusion equations, is approximated on an evolving cell boundary using ...
Neilson, Matthew Paterson +3 more
core +3 more sources
Knockdown of klotho Leads to Cell Movement Impairment during Zebrafish Gastrulation
Fishes, 2023 (1) Background: Klotho is a multifunctional protein, but its biophysiological roles during fish early development are unclear. (2) Methods: We carried out anti-sense Klotho morpholino injection and whole-mount in situ hybridization experiments in this ...
Heng-Chih Pan +6 more
doaj +1 more source
Local cell interactions and self-amplifying individual cell ingression drive amniote gastrulation
eLife, 2014 Gastrulation generates three layers of cells (ectoderm, mesoderm, endoderm) from a single sheet, while large scale cell movements occur across the entire embryo.
Octavian Voiculescu +3 more
doaj +1 more source
Modelling cell movement, cell differentiation, cell sorting and proportion regulation in Dictyostelium discoideum aggregations [PDF]
, 2015 Understanding the mechanisms that control tissue morphogenesis and homeostasis is a central goal not only in developmental biology but also has great relevance for our understanding of various diseases, including cancer.
Weijer, C. J.; id_orcid +2 more
core +1 more source
The Birth of the Eye Vesicle: When Fate Decision Equals Morphogenesis
Frontiers in Neuroscience, 2018 As the embryonic ectoderm is induced to form the neural plate, cells inside this epithelium acquire restricted identities that will dictate their behavior and progressive differentiation.
Florence A. Giger, Corinne Houart
doaj +1 more source
MicroRNA-16 inhibits cell proliferation and migration by targeting heat shock protein 70 in heat-denatured dermal fibroblasts [PDF]
The Korean Journal of Internal Medicine, 2019 Background/Aims This study aimed to investigate the precise mechanism and function of miR-16 in heat-denatured primary human dermal fibroblasts. Methods Primary human dermal fibroblasts were separated from normal human skin samples.
Chun Zhang +4 more
doaj +1 more source
In vivo movement of the type V myosin Myo52 requires dimerisation but is independent of the neck domain [PDF]
, 2007 Intracellular movement is a fundamental property of all cell types. Many organelles and molecules are actively transported throughout the cytoplasm by molecular motors, such as the dimeric type V myosins.
Mulvihill, Daniel P. +6 more
core +1 more source
Patterns of cell movement within the Dictyostelium slug revealed by cell type-specific, surface labeling of living cells [PDF]
, 1994 There are cells acattered in the rear, prespore region of the Dictyostelium slug that share many of the properties of the prestalk cells and that are therefore called anterior-like cells (ALCs).
Early, Anne +4 more
core +1 more source
Inhibition of colorectal cancer cell proliferation, invasion, and migration, and induction of epithelial-mesenchymal transition via TFF1 silencing [PDF]
Vojnosanitetski PregledBackground/Aim. The identification of aberrant genes associated with colorectal cancer (CRC) and understanding their pathogenic mechanisms are important for early diagnosis and the determination of appropriate therapy.
Zhao Jing +7 more
doaj +1 more source
A gradient method for the quantitative analysis of cell movement and tissue flow and its application to the analysis of multicellular Dictyostelium development [PDF]
, 1994 We describe the application of a novel image processing method, which allows quantitative analysis of cell and tissue movement in a series of digitized video images. The result is a vector velocity field showing average direction and velocity of movement
Nomura, Atsushi +3 more
core +1 more source