Results 41 to 50 of about 72,615 (309)
eLife, 2017 The neural crest is a dynamic progenitor cell population that arises at the border of neural and non-neural ectoderm. The inductive roles of FGF, Wnt, and BMP at the neural plate border are well established, but the signals required for subsequent neural
Christie Ciarlo +11 more
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Beta-actin is required for proper mouse neural crest ontogeny. [PDF]
PLoS ONE, 2014 The mouse genome consists of six functional actin genes of which the expression patterns are temporally and spatially regulated during development and in the adult organism. Deletion of beta-actin in mouse is lethal during embryonic development, although
Davina Tondeleir +3 more
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Cell, 2010 The neural crest is a transient population of cells that emerges from the neural tube during the early stages of embryonic development. Neural crest cells are unique to vertebrates and have properties similar to stem cells, including the ability to differentiate into many cell types (i.e., multipotency) and to regenerate.
Sauka-Spengler, T, Bronner, M
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Evolution Letters, 2021 The neural crest hypothesis posits that selection for tameness resulted in mild alterations to neural crest cells during embryonic development, which directly or indirectly caused the appearance of traits associated with the “domestication syndrome” (DS).
Laura A. B. Wilson +4 more
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Annexin a6 modulates chick cranial neural crest cell emigration. [PDF]
PLoS ONE, 2012 The vertebrate neural crest is a population of migratory cells that originates in the dorsal aspect of the embryonic neural tube. These cells undergo an epithelial-to-mesenchymal transition (EMT), delaminate from the neural tube and migrate extensively ...
Chyong-Yi Wu, Lisa A Taneyhill
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Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel +15 more
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Posteriorizing factor Gbx2 is a direct target of Wnt signalling during neural crest induction [PDF]
, 2015 Wnt signalling is required for neural crest induction; however the direct targets of the Wnt pathway during neural crest induction remain unknown. I show here that the homeobox gene Gbx2 is essential in this process and is directly activated by Wnt/β ...
Li, B
core
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Defining properties of neural crest-derived progenitor cells from the apex of human developing tooth [PDF]
, 2008 The connective tissue of the human tooth arises from cells that are derived from the cranial neural crest and, thus, are termed as "ectomesenchymal cells." Here, cells being located in a pad-like tissue adjacent to the apex of the developing tooth, which
Götz, Werner +6 more
core
A novel role for Lh3 dependent ECM modifications during neural crest cell migration in zebrafish. [PDF]
PLoS ONE, 2013 During vertebrate development, trunk neural crest cells delaminate along the entire length of the dorsal neural tube and initially migrate as a non-segmented sheet.
Santanu Banerjee +3 more
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