Results 31 to 40 of about 72,615 (309)

Neural crest-derived mesenchymal cells require Wnt signaling for their development and drive invagination of the telencephalic midline. [PDF]

open access: yesPLoS ONE, 2014
Embryonic neural crest cells contribute to the development of the craniofacial mesenchyme, forebrain meninges and perivascular cells. In this study, we investigated the function of ß-catenin signaling in neural crest cells abutting the dorsal forebrain ...
Youngshik Choe   +2 more
doaj   +1 more source

Cardiovascular Development and the Colonizing Cardiac Neural Crest Lineage

open access: yesThe Scientific World Journal, 2007
Although it is well established that transgenic manipulation of mammalian neural crest-related gene expression and microsurgical removal of premigratory chicken and Xenopus embryonic cardiac neural crest progenitors results in a wide spectrum of both ...
Paige Snider   +3 more
doaj   +1 more source

Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin

open access: yesFrontiers in Cell and Developmental Biology, 2023
Neural crest-derived cells play essential roles in skin function and homeostasis. However, how they interact with environmental cues and differentiate into functional skin cells remains unclear.
Shize Ma   +13 more
doaj   +1 more source

Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration

open access: yeseLife, 2020
During gastrulation, neural crest cells are specified at the neural plate border, as characterized by Pax7 expression. Using single-cell RNA sequencing coupled with high-resolution in situ hybridization to identify novel transcriptional regulators, we ...
Shashank Gandhi   +5 more
doaj   +1 more source

GSK3 and lamellipodin balance lamellipodial protrusions and focal adhesion maturation in mouse neural crest migration

open access: yesCell Reports, 2023
Summary: Neural crest cells are multipotent cells that delaminate from the neuroepithelium, migrating throughout the embryo. Aberrant migration causes developmental defects.
Lisa Dobson   +6 more
doaj   +1 more source

Regulation of boundary cap neural crest stem cell differentiation after transplantation [PDF]

open access: yes, 2009
Success of cell replacement therapies for neurological disorders will depend largely on the optimization of strategies to enhance viability and control the developmental fate of stem cells after transplantation.
Hjerling-Leffler, J   +19 more
core   +1 more source

Adipose stromal cells contain phenotypically distinct adipogenic progenitors derived from neural crest. [PDF]

open access: yesPLoS ONE, 2013
Recent studies have shown that adipose-derived stromal/stem cells (ASCs) contain phenotypically and functionally heterogeneous subpopulations of cells, but their developmental origin and their relative differentiation potential remain elusive.
Yoshihiro Sowa   +6 more
doaj   +1 more source

The heart of the neural crest: cardiac neural crest cells in development and regeneration [PDF]

open access: yesDevelopment, 2020
ABSTRACT Cardiac neural crest cells (cNCCs) are a migratory cell population that stem from the cranial portion of the neural tube. They undergo epithelial-to-mesenchymal transition and migrate through the developing embryo to give rise to portions of the outflow tract, the valves and the arteries of the heart.
Rajani M. George   +2 more
openaire   +2 more sources

Retroviral lineage analysis reveals dual contribution from ectodermal placodes and neural crest cells to avian olfactory sensory and GnRH neurons

open access: yesNatural Sciences, 2022
The origin of the neurons and glia in the olfactory system of vertebrates has been controversial, with different cell types attributed to being of ectodermal placode versus neural crest lineage, depending upon the species.
Alison Koontz   +2 more
doaj   +1 more source

Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish

open access: yeseLife, 2019
Cardiac neural crest cells contribute to important portions of the cardiovascular system including the aorticopulmonary septum and cardiac ganglion. Using replication incompetent avian retroviruses for precise high-resolution lineage analysis, we uncover
Weiyi Tang   +3 more
doaj   +1 more source

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