Results 31 to 40 of about 72,346 (309)

Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration

eLife, 2020
During gastrulation, neural crest cells are specified at the neural plate border, as characterized by Pax7 expression. Using single-cell RNA sequencing coupled with high-resolution in situ hybridization to identify novel transcriptional regulators, we ...
Shashank Gandhi, Erica J Hutchins, Krystyna Maruszko, Jong H Park, Matthew Thomson, Marianne E Bronner   +5 more
doaj   +1 more source

Regulation of boundary cap neural crest stem cell differentiation after transplantation [PDF]

, 2009
Success of cell replacement therapies for neurological disorders will depend largely on the optimization of strategies to enhance viability and control the developmental fate of stem cells after transplantation.
Hjerling-Leffler, J, Aldskogius, Hakan, Wegner, M, Hjerling-Leffler, Jens, Kozlova, Elena N, Medvinsky, Alexander, Berens, C, Aldskogius, H, Kozlova, EN, Berens, Christian, Kanaykina, Nadezda, Sandelin, Martin, Schreiner, S, Wegner, Michael, Kanaykina, N, Sandelin, M, Liakhovitskaia, A, Medvinsky, A, Liakhovitskaia, Anna, Schreiner, Silke   +19 more
core   +1 more source

GSK3 and lamellipodin balance lamellipodial protrusions and focal adhesion maturation in mouse neural crest migration

Cell Reports, 2023
Summary: Neural crest cells are multipotent cells that delaminate from the neuroepithelium, migrating throughout the embryo. Aberrant migration causes developmental defects.
Lisa Dobson, William B. Barrell, Zahra Seraj, Steven Lynham, Sheng-Yuan Wu, Matthias Krause, Karen J. Liu   +6 more
doaj   +1 more source

The heart of the neural crest: cardiac neural crest cells in development and regeneration [PDF]

Development, 2020
ABSTRACT Cardiac neural crest cells (cNCCs) are a migratory cell population that stem from the cranial portion of the neural tube. They undergo epithelial-to-mesenchymal transition and migrate through the developing embryo to give rise to portions of the outflow tract, the valves and the arteries of the heart.
Rajani M. George, Gabriel Maldonado-Velez, Anthony B. Firulli   +2 more
openaire   +2 more sources

Adipose stromal cells contain phenotypically distinct adipogenic progenitors derived from neural crest. [PDF]

PLoS ONE, 2013
Recent studies have shown that adipose-derived stromal/stem cells (ASCs) contain phenotypically and functionally heterogeneous subpopulations of cells, but their developmental origin and their relative differentiation potential remain elusive.
Yoshihiro Sowa, Tetsuya Imura, Toshiaki Numajiri, Kosuke Takeda, Yo Mabuchi, Yumi Matsuzaki, Kenichi Nishino   +6 more
doaj   +1 more source

Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish

eLife, 2019
Cardiac neural crest cells contribute to important portions of the cardiovascular system including the aorticopulmonary septum and cardiac ganglion. Using replication incompetent avian retroviruses for precise high-resolution lineage analysis, we uncover
Weiyi Tang, Megan L Martik, Yuwei Li, Marianne E Bronner   +3 more
doaj   +1 more source

Beta-actin is required for proper mouse neural crest ontogeny. [PDF]

PLoS ONE, 2014
The mouse genome consists of six functional actin genes of which the expression patterns are temporally and spatially regulated during development and in the adult organism. Deletion of beta-actin in mouse is lethal during embryonic development, although
Davina Tondeleir, Rivka Noelanders, Karima Bakkali, Christophe Ampe   +3 more
doaj   +1 more source

SnapShot: Neural Crest

Cell, 2010
The neural crest is a transient population of cells that emerges from the neural tube during the early stages of embryonic development. Neural crest cells are unique to vertebrates and have properties similar to stem cells, including the ability to differentiate into many cell types (i.e., multipotency) and to regenerate.
Sauka-Spengler, T, Bronner, M
openaire   +3 more sources

A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development

eLife, 2017
The neural crest is a dynamic progenitor cell population that arises at the border of neural and non-neural ectoderm. The inductive roles of FGF, Wnt, and BMP at the neural plate border are well established, but the signals required for subsequent neural
Christie Ciarlo, Charles K Kaufman, Beste Kinikoglu, Jonathan Michael, Song Yang, Christopher D′Amato, Sasja Blokzijl-Franke, Jeroen den Hertog, Thorsten M Schlaeger, Yi Zhou, Eric Liao, Leonard I Zon   +11 more
doaj   +1 more source

Annexin a6 modulates chick cranial neural crest cell emigration. [PDF]

PLoS ONE, 2012
The vertebrate neural crest is a population of migratory cells that originates in the dorsal aspect of the embryonic neural tube. These cells undergo an epithelial-to-mesenchymal transition (EMT), delaminate from the neural tube and migrate extensively ...
Chyong-Yi Wu, Lisa A Taneyhill
doaj   +1 more source