Results 51 to 60 of about 64,865 (357)
Due to its long history, the study of human gross anatomy has not adequately incorporated modern embryological findings; consequently, the current understanding has often been incompatible with recent discoveries from molecular studies.
Shunsaku Homma +5 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Spatiotemporal oscillations of Notch1, Dll1 and NICD are coordinated across the mouse PSM [PDF]
During somitogenesis, epithelial somites form from the pre-somitic mesoderm (PSM) in a periodic manner. This periodicity is regulated by a molecular oscillator, known as the 'segmentation clock', that is characterised by an oscillatory pattern of gene ...
Dale, J. Kim +7 more
core +1 more source
Adult-onset degeneration of adipose tissue in mice deficient for the Sox8 transcription factor
Although the transcription factor Sox8 is broadly expressed during embryogenesis in developing ectodermal and mesodermal tissues, mice develop surprisingly normally in the absence of Sox8.
Sabine I.E. Guth +3 more
doaj +1 more source
Complete Dorsal Pancreatic Agenesis and Unilateral Renal Agenesis: First Case Report and Review of Literature [PDF]
Dorsal pancreatic agenesis is very rare congenital anomaly of pancreas. Patients with this anomaly are usually asymptomatic or may present with abdominal pain or acute or chronic pancreatitis.
Manjit Motilal Bagul, Purva Traipathi
doaj +1 more source
Advanced imaging techniques reveal details of the interactions between the two layers of the embryonic midgut that influence its ultimate shape.
Danelle Devenport
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Tukushi modulates Xnr2, FGF, and and BMP signalling: Regulation of Xenopus Germ Layer Formation [PDF]
BACKGROUND: Cell-cell communication is essential in tissue patterning. In early amphibian development, mesoderm is formed in the blastula-stage embryo through inductive interactions in which vegetal cells act on overlying equatorial cells. Members of the
Ohta, K +4 more
core
Directional mesoderm cell migration in the Xenopus gastrula [PDF]
The movement of the dorsal mesoderm across the blastocoel roof of the Xenopus gastrula is examined. We show that different parts of the mesoderm which can be distinguished by their morphogenetic behavior in the embryo are all able to migrate ...
Winklbauer, R. ; https://orcid.org/ +1 more
core +1 more source
Gastrulation denotes a very important developmental process, which includes significant structural tissue rearrangements and patterning events that shape the emerging vertebrate organism.
Jennifer Kreis +4 more
doaj +1 more source

