Results 1 to 10 of about 55,791 (279)
PI3K/Akt1 signalling specifies foregut precursors by generating regionalized extra-cellular matrix
eLife, 2013 During embryonic development signalling pathways act repeatedly in different contexts to pattern the emerging germ layers. Understanding how these different responses are regulated is a central question for developmental biology.
S Nahuel Villegas +7 more
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In vitro Symbiosis of Reef-Building Coral Cells With Photosynthetic Dinoflagellates
Frontiers in Marine Science, 2021 Coral reefs are the biodiversity hot spots of the oceans, but they have suffered from increasing environmental stresses caused principally by anthropogenic global warming.
Kaz Kawamura +6 more
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Retinoic acid is required for endodermal pouch morphogenesis and not for pharyngeal endoderm specification [PDF]
Developmental Dynamics, 2006 AbstractLateral view of the head of a 30 hours post fertilization Tg(foxd3:gfp) zebrafish embryo expressing GFP in neural crest cells which will differentiate into pigment cells and cells in the pharyngeal arches (anterior is pointing up). The embryo is double labeled with the antibody Zn8 in red, which labels four endodermal pouches in between neural ...
Daniel, Kopinke +4 more
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FEBS Open Bio, 2021 Thyroid dysgenesis (TD) is a major cause of primary congenital hypothyroidism; however, the molecular mechanism underlying this process is unclear.
Rui‐jia Zhang +6 more
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Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm
eLife, 2017 Nodal is considered the key inducer of mesendoderm in vertebrate embryos and embryonic stem cells. Other TGF-beta-related signals, such as Vg1/Dvr1/Gdf3, have also been implicated in this process but their roles have been unclear or controversial.
Tessa G Montague, Alexander F Schier
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Frontiers in Cell and Developmental Biology, 2021 Vertebrate dentitions arise at various places within the oropharyngeal cavity including the jaws, the palate, or the pharynx. These dentitions develop in a highly organized way, where new tooth germs are progressively added adjacent to the initiator ...
Vladimír Soukup +8 more
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Cells, 2021 Medullary thyroid carcinoma contributes to about 3–4% of thyroid cancers and affects C cells rather than follicular cells. Thyroid C cell differentiation from human pluripotent stem cells has not been reported.
Kwaku Dad Abu-Bonsrah +2 more
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eLife, 2020 Lineage specification is governed by gene regulatory networks (GRNs) that integrate the activity of signaling effectors and transcription factors (TFs) on enhancers.
Shreyasi Mukherjee +11 more
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Stem Cell Reports, 2018 Summary: Early endoderm progenitors naturally possess robust propagating potential to develop a majority of meter-long gastrointestinal tracts and are therefore considered as a promising source for therapy.
Ran-Ran Zhang +8 more
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Formation of a polarised primitive endoderm layer in embryoid bodies requires fgfr/erk signalling.
PLoS ONE, 2014 The primitive endoderm arises from the inner cell mass during mammalian pre-implantation development. It faces the blastocoel cavity and later gives rise to the extraembryonic parietal and visceral endoderm.
Gail Doughton +4 more
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