Results 1 to 10 of about 40,613 (248)

Endothelial cells instruct liver specification of embryonic stem cell-derived endoderm through endothelial VEGFR2 signaling and endoderm epigenetic modifications

open access: yesStem Cell Research, 2018
Liver organogenesis requires complex cell-cell interactions between hepatic endoderm cells and adjacent cell niches. Endothelial cells are key players for endoderm hepatic fate decision. We previously demonstrated that the endothelial cell niche promotes
Songyan Han   +5 more
doaj   +2 more sources

Insights Into Human Development and Disease From Human Pluripotent Stem Cell Derived Intestinal Organoids

open access: yesFrontiers in Medicine, 2019
In recent years, advances in human pluripotent stem cell (hPSC) biology have enabled the generation of gastrointestinal (GI) organoids which recapitulate aspects of normal organ development.
Abdelkader Daoud, Jorge O. Múnera
doaj   +1 more source

Endoderm-Derived Myeloid-like Metaphocytes in Zebrafish Gill Mediate Soluble Antigen-Induced Immunity

open access: yesCell Reports, 2020
Summary: Immune cells in the mucosal barriers of vertebrates are highly heterogeneous in their origin and function. This heterogeneity is further exemplified by the recent discovery of ectoderm-derived immune cells—metaphocytes in zebrafish epidermis ...
Xi Lin   +4 more
doaj   +1 more source

The lncRNA DEANR1 Facilitates Human Endoderm Differentiation by Activating FOXA2 Expression

open access: yesCell Reports, 2015
Long non-coding RNAs (lncRNAs) regulate diverse biological processes, including cell lineage specification. Here, we report transcriptome profiling of human endoderm and pancreatic cell lineages using purified cell populations.
Wei Jiang   +4 more
doaj   +1 more source

GATA6 is essential for endoderm formation from human pluripotent stem cells

open access: yesBiology Open, 2017
Protocols have been established that direct differentiation of human pluripotent stem cells into a variety of cell types, including the endoderm and its derivatives. This model of differentiation has been useful for investigating the molecular mechanisms
J. B. Fisher   +3 more
doaj   +1 more source

Complete Dorsal Pancreatic Agenesis and Unilateral Renal Agenesis: First Case Report and Review of Literature [PDF]

open access: yesInternational Journal of Anatomy Radiology and Surgery, 2016
Dorsal pancreatic agenesis is very rare congenital anomaly of pancreas. Patients with this anomaly are usually asymptomatic or may present with abdominal pain or acute or chronic pancreatitis.
Manjit Motilal Bagul, Purva Traipathi
doaj   +1 more source

A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation

open access: yeseLife, 2020
Long noncoding RNAs (lncRNAs) are a heterogenous group of RNAs, which can encode small proteins. The extent to which developmentally regulated lncRNAs are translated and whether the produced microproteins are relevant for human development is unknown ...
Bjoern Gaertner   +10 more
doaj   +1 more source

Corn root morphoanatomy at different development stages and yield under water stress [PDF]

open access: yesPesquisa Agropecuária Brasileira, 2016
: The objective of this work was to characterize the morphoanatomy of roots and the yield traits of two corn hybrids contrasting for drought tolerance (DKB 390, tolerant; and BRS 1030, sensitive), at different stages of development.
Thiago Corrêa de Souza   +4 more
doaj   +1 more source

A case report of craniovertebral junction intradural extramedullary neurenteric cyst

open access: yesMedical Journal of Dr. D.Y. Patil University, 2014
A neurenteric cyst of the craniocervical (CV) junction, as a cause of bulbomedullary compression, is very rare. An abnormal communication between the endoderm and neuroectoderm during the third week of embryogenesis may be responsible for its formation ...
Rajeshwari S Vhora   +3 more
doaj   +1 more source

Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development. [PDF]

open access: yesPLoS ONE, 2013
Mouse embryos lacking the polycomb group gene member Yin-Yang1 (YY1) die during the peri-implantation stage. To assess the post-gastrulation role of YY1, a conditional knock-out (cKO) strategy was used to delete YY1 from the visceral endoderm of the yolk
Siyeon Rhee   +5 more
doaj   +1 more source

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