Results 31 to 40 of about 39,578 (195)

Endoderm development - from patterning to organogenesis [PDF]

open access: yes
Although the ectoderm and mesoderm have been the focus of intensive work in the recent era of studies on the molecular control of vertebrate development, the endoderm has received less attention.
Melton, D. A., Grapin-Botton, A.
core   +1 more source

scTIDE: Deciphering Critical Transitions Through Cell‐Perturbed Manifold Graphs and Optimal Transport Conditional Flow Matching

open access: yesAdvanced Science, EarlyView.
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong   +6 more
wiley   +1 more source

A perspective from the Mesozoic: Evolutionary changes of the mammalian skull and their influence on feeding efficiency and high‐frequency hearing

open access: yesThe Anatomical Record, EarlyView.
Abstract The complex evolutionary history behind modern mammalian chewing performance and hearing function is a result of several changes in the entire skeletomuscular system of the skull and lower jaw. Lately, exciting multifunctional 3D analytical methods and kinematic simulations of feeding functions in both modern and fossil mammals and their ...
Julia A. Schultz
wiley   +1 more source

VegT initiates endoderm formation [PDF]

open access: yes, 2001
During cleavage stages, maternal VegT mRNA and protein are localized to the Xenopus embryo's vegetal region from which the endoderm will arise and where several zygotic gene transcripts will be localized.
Jennifer B Xanthos   +4 more
core  

Insight into Nephrocan function in mouse endoderm patterning [PDF]

open access: yes, 2021
Endoderm-derived organs as the liver and pancreas are potential targets for regenerative therapies, and so there is great interest in understanding the pathways that regulate the induction and specification of this germ layer. Currently, the knowledge of
Addeo, Martina
core  

Insight into Nephrocan Function in Mouse Endoderm Patterning [PDF]

open access: yes, 2019
Endoderm-derived organs as liver and pancreas are potential targets for regenerative therapies, and thus, there is great interest in understanding the pathways that regulate the induction and specification of this germ layer.
Antonio Marino   +15 more
core   +4 more sources

Establishment of Interspecies Somatic Cell Nuclear Transfer and Transgene‐Free Inducible Pluripotent Stem Cells for Versatile Conservation of the Germplasm Resource of Wild Boar

open access: yesAnimal Research and One Health, EarlyView.
Conserving genetic material and even increasing genetic diversity is critical. To conduct the conservation of wild boar germplasm resources, we have successfully obtained healthy cloned wild boars for the first time using interspecies somatic cell nuclear transfer and established transgene‐free iPSCs that can be used to conduct iterative rounds of gene
Chen Gao   +11 more
wiley   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin   +5 more
wiley   +1 more source

Characterisation of a novel in vitro model of definitive endoderm development and a novel definitive endoderm gene marker [PDF]

open access: yes, 2012
© 2012 Dr. Hwee Ngee GohThe definitive endoderm, one of the primary germ lineages generated during early development, is the forerunner cell population that contributes to the formation of the gastrointestinal and respiratory tract and their associated ...
GOH, HWEE NGEE
core  

Retinoic Acid and the Development of the Endoderm [PDF]

open access: yesJournal of Developmental Biology, 2015
Retinoic acid (RA) is an important signaling molecule in the development of the endoderm and an important molecule in protocols used to generate endodermal cell types from stem cells. In this review, we describe the RA signaling pathway and its role in the patterning and specification of the extra embryonic endoderm and different endodermal organs. The
Kelly, Gregory M., Drysdale, Thomas A.
openaire   +4 more sources

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