Results 31 to 40 of about 55,791 (279)
Mature Mediastinal Teratoma [PDF]
Journal of Clinical and Diagnostic Research, 2015 A teratoma is a tumour with tissue or organ components resembling normal derivatives of more than one germ layer. We present a case of mediastinal mature teratoma as they have a low incidence rate.
Chikka Narasimhaiah Anushree +1 more
doaj +1 more source
Cell-state transitions and collective cell movement generate an endoderm-like region in gastruloids
bioRxiv, 2020 Shaping the animal body plan is a complex process that involves the spatial organization and patterning of different layers of cells. Recent advances in live imaging have started to unravel the cellular choreography underlying this process in mammals ...
Ali Hashmi +7 more
semanticscholar +1 more source
The emergent landscape of the mouse gut endoderm at single-cell resolution
Nature, 2019 Here we delineate the ontogeny of the mammalian endoderm by generating 112,217 single-cell transcriptomes, which represent all endoderm populations within the mouse embryo until midgestation.
Sonja Nowotschin +13 more
semanticscholar +1 more source
In Vivo Regulation of the Zebrafish Endoderm Progenitor Niche by T-Box Transcription Factors
Cell Reports, 2017 T-box transcription factors T/Brachyury homolog A (Ta) and Tbx16 are essential for correct mesoderm development in zebrafish. The downstream transcriptional networks guiding their functional activities are poorly understood.
Andrew C. Nelson +5 more
doaj +1 more source
In vitro generation of human pluripotent stem cell derived lung organoids
eLife, 2015 Recent breakthroughs in 3-dimensional (3D) organoid cultures for many organ systems have led to new physiologically complex in vitro models to study human development and disease.
Briana R Dye +12 more
doaj +1 more source
Investigating the molecular guts of endoderm formation using zebrafish [PDF]
, 2021 The vertebrate endoderm makes major contributions to the respiratory and gastrointestinal tracts and all associated organs. Zebrafish and humans share a high degree of genetic homology and strikingly similar endodermal organ systems.
Figiel, Daniela M. +2 more
core +1 more source
Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes
eLife, 2017 The evolutionary origins of the hypoxia-sensitive cells that trigger amniote respiratory reflexes – carotid body glomus cells, and ‘pulmonary neuroendocrine cells’ (PNECs) - are obscure.
Dorit Hockman +16 more
doaj +1 more source
Frontiers in Medicine, 2019 In recent years, advances in human pluripotent stem cell (hPSC) biology have enabled the generation of gastrointestinal (GI) organoids which recapitulate aspects of normal organ development.
Abdelkader Daoud, Jorge O. Múnera
doaj +1 more source
GATA6-AS1 Regulates GATA6 Expression to Modulate Human Endoderm Differentiation
Stem Cell Reports, 2020 Summary Transcriptome analysis has uncovered a series of long noncoding RNAs (lncRNAs) transcribed during cell differentiation, but how lncRNA is integrated with known transcriptional regulatory network is poorly understood.
Jie Yang +5 more
semanticscholar +1 more source
Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development. [PDF]
PLoS ONE, 2013 Mouse embryos lacking the polycomb group gene member Yin-Yang1 (YY1) die during the peri-implantation stage. To assess the post-gastrulation role of YY1, a conditional knock-out (cKO) strategy was used to delete YY1 from the visceral endoderm of the yolk
Siyeon Rhee +5 more
doaj +1 more source