Results 51 to 60 of about 40,613 (248)
Vertebrate intestinal endoderm development [PDF]
Developmental Dynamics, 2011 AbstractThe endoderm gives rise to the lining of the esophagus, stomach and intestines, as well as associated organs. To generate a functional intestine, a series of highly orchestrated developmental processes must occur. In this review, we attempt to cover major events during intestinal development from gastrulation to birth, including endoderm ...
Jason R, Spence +2 more
openaire +2 more sources
Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays
Advanced Science, EarlyView.ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen +13 more
wiley +1 more source
Frontiers in Cell and Developmental Biology, 2021 Vertebrate dentitions arise at various places within the oropharyngeal cavity including the jaws, the palate, or the pharynx. These dentitions develop in a highly organized way, where new tooth germs are progressively added adjacent to the initiator ...
Vladimír Soukup +8 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley +1 more source
The Anatomical Record, EarlyView.Abstract The complex evolutionary history behind modern mammalian chewing performance and hearing function is a result of several changes in the entire skeletomuscular system of the skull and lower jaw. Lately, exciting multifunctional 3D analytical methods and kinematic simulations of feeding functions in both modern and fossil mammals and their ...
Julia A. Schultz
wiley +1 more source
Wnt signaling specifies and patterns intestinal endoderm
, 2011 Wnt signaling has been implicated in many developmental processes, but its role in early endoderm development is not well understood. Wnt signaling is active in posterior endoderm as early as E7.5.
Maehr, Rene +7 more
core +1 more source
Insight into Nephrocan function in mouse endoderm patterning [PDF]
, 2021 Endoderm-derived organs as the liver and pancreas are potential targets for regenerative therapies, and so there is great interest in understanding the pathways that regulate the induction and specification of this germ layer. Currently, the knowledge of
Addeo, Martina
core
Insight into Nephrocan Function in Mouse Endoderm Patterning [PDF]
, 2019 Endoderm-derived organs as liver and pancreas are potential targets for regenerative therapies, and thus, there is great interest in understanding the pathways that regulate the induction and specification of this germ layer.
Antonio Marino +15 more
core +2 more sources
Cells, 2021 Medullary thyroid carcinoma contributes to about 3–4% of thyroid cancers and affects C cells rather than follicular cells. Thyroid C cell differentiation from human pluripotent stem cells has not been reported.
Kwaku Dad Abu-Bonsrah +2 more
doaj +1 more source
Animal Research and One Health, EarlyView.Conserving genetic material and even increasing genetic diversity is critical. To conduct the conservation of wild boar germplasm resources, we have successfully obtained healthy cloned wild boars for the first time using interspecies somatic cell nuclear transfer and established transgene‐free iPSCs that can be used to conduct iterative rounds of gene
Chen Gao +11 more
wiley +1 more source