Results 51 to 60 of about 55,791 (279)

BMP signaling induces visceral endoderm differentiation of XEN cells and parietal endoderm [PDF]

, 2012
The extraembryonic endoderm of mammals is essential for nutritive support of the fetus and patterning of the early embryo. Visceral and parietal endoderm are major subtypes of this lineage with the former exhibiting most, if not all, of the embryonic ...
Kunath, Tilo, Cheryle A. Séguin, Ryczko, Michael, Tilo Kunath, Rodriguez, Tristan A., Tristan A. Rodriguez, Agnieszka Paca, Paca, Agnieszka, Séguin, Cheryle A., Clements, Melanie, Melanie Clements, Michael Ryczko, Janet Rossant, Rossant, Janet   +13 more
core   +1 more source

Pharyngeal endoderm development

, 2023
AnnData object of scRNA-seq dataset of pharyngeal endoderm development data.
Michal Klein (9349343), Philipp Weiler (12855479), Marius Lange (9348875)   +2 more
core   +1 more source

Mechanisms of endoderm formation in a cartilaginous fish reveal ancestral and homoplastic traits in jawed vertebrates

Biology Open, 2014
In order to gain insight into the impact of yolk increase on endoderm development, we have analyzed the mechanisms of endoderm formation in the catshark S. canicula, a species exhibiting telolecithal eggs and a distinct yolk sac.
Benoit G. Godard, Marion Coolen, Sophie Le Panse, Aurélie Gombault, Susana Ferreiro-Galve, Laurent Laguerre, Ronan Lagadec, Patrick Wincker, Julie Poulain, Corinne Da Silva, Shigehiro Kuraku, Wilfrid Carre, Agnès Boutet, Sylvie Mazan   +13 more
doaj   +1 more source

Endoderm differentiation of tWT and dKO hESCs.

, 2022
A, A schematic drawing of the endoderm differentiation. B, Relative expression levels of representative genes during the endoderm differentiation. Box-plot elements are described in Fig 1. n = 7 from three different experiments.
Shota Nakanoh (9071402), An-Sofie Lenaerts (210471), Carola Maria Morell (14159951), Laetitia Pinte (10142636), Ludovic Vallier (75166), Juned Kadiwala (9071390)   +5 more
core   +1 more source

A desert lncRNA HIDEN regulates human endoderm differentiation via interacting with IMP1 and stabilizing FZD5 mRNA

Genome Biology, 2023
Background Extensive studies have revealed the function and mechanism of lncRNAs in development and differentiation, but the majority have focused on those lncRNAs adjacent to protein-coding genes.
Pei Lu, Jie Yang, Mao Li, Shanshan Wen, Tianzhe Zhang, Chenchao Yan, Ran Liu, Yu Xiao, Xinghuan Wang, Wei Jiang   +9 more
doaj   +1 more source

GATA6 Plays an Important Role in the Induction of Human Definitive Endoderm, Development of the Pancreas, and Functionality of Pancreatic β Cells

Stem Cell Reports, 2017
Summary Induced pluripotent stem cells were created from a pancreas agenesis patient with a mutation in GATA6. Using genome-editing technology, additional stem cell lines with mutations in both GATA6 alleles were generated and demonstrated a severe block
Amita Tiyaboonchai, Fabian L. Cardenas-Diaz, Lei Ying, J. Maguire, X. Sim, Chintan D. Jobaliya, Alyssa L. Gagne, Siddharth Kishore, Diana E. Stanescu, Nkecha Hughes, D. D. De León, Deborah L. French, Paul J Gadue   +12 more
semanticscholar   +1 more source

Self‐Assembled Pt(II) Complexes Boost Up Stem Cell Proliferation and Accelerate Metamorphosis in Living Organisms

Angewandte Chemie, EarlyView.
Pt1, an organometallic platinum‐based complex, act as a modulator of redox homeostasis in cnidarians, regulating cellular functions and life‐cycle dynamics. In Nematostella vectensis, it mitigates oxidative stress, strengthens detox systems and accelerates development.
Giuseppina Tommasini, Tania Pecoraro, Anna Lewinska, Maciej Wnuk, Olga Kolodziej, Daniela Intartaglia, Simona Morgera, Alessandro Aliprandi, Giulia Veronesi, Giorgio Facchetti, Isabella Rimoldi, Angela Tino, Claudia Tortiglione, Luisa De Cola   +13 more
wiley   +2 more sources

Effect of Hepatic Differentiation on Fatty Acid Composition of Induced Pluripotent Stem Cells Derived from Human Dermal Fibroblasts

İstanbul Medical Journal, 2018
Introduction: Human induced pluripotent stem cells (hiPSCs) have been recognized as key progenitor cells for liver regeneration, which could potentially be used in the repair of liver injury.
Nasim Parsafam, Yagoub Rahimi, Amir Mehdizadeh, Hojjatollah Nozad Charoudeh, Mohammad Nouri, Maghsod Shaaker, Masoud Darabi   +6 more
doaj   +1 more source

Genome-Wide Epigenetic Characterization of Tissues from Three Germ Layers Isolated from Sheep Fetuses

Frontiers in Genetics, 2017
DNA methylation of regulatory and growth-related genes contributes to fetal programming which is important for maintaining the correct development of three germ layers of the embryo that develope into different tissues and organs, and which persists into
Emanuele Capra, Paola Toschi, Marcello Del Corvo, Marcello Del Corvo, Barbara Lazzari, Barbara Lazzari, Pier A. Scapolo, Pasqualino Loi, John L. Williams, Alessandra Stella, Alessandra Stella, Paolo Ajmone-Marsan   +11 more
doaj   +1 more source

Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal [PDF]

, 2006
In Xenopus, the establishment of the anteroposterior axis involves two key signalling pathways, canonical Wnt and Nodal-related TGFbeta. There are also a number of transcription factors that feedback upon these pathways.
Gardner, Clare E, Clare E. Gardner, Geoffrey I. Johnston, Brickman, Joshua M, Andrea L. Zamparini, Tim Watts, Zamparini, Andrea L, Tomlinson, Simon R, Watts, Tim, Joshua M. Brickman, Johnston, Geoffrey I, Simon R. Tomlinson   +11 more
core   +1 more source