Results 1 to 10 of about 35,082 (162)

SARS-CoV-2 pseudoparticles preferentially infect ectoderm in human embryonic tissues [PDF]

Frontiers in Cell and Developmental Biology
IntroductionThe early stages of human embryonic development are challenging to study in pregnant women.MethodsA “disease-in-a-dish” model was utilized to investigate SARS-CoV-2 infection of human embryonic stem cells and the three germ layers (ectoderm ...
Ann Song, Ann Song, Prue Talbot
doaj   +2 more sources

Transcriptional Profiling of Ectoderm Specification to Keratinocyte Fate in Human Embryonic Stem Cells [PDF]

PLoS ONE, 2015
In recent years, several studies have shed light into the processes that regulate epidermal specification and homeostasis. We previously showed that a broad-spectrum γ-secretase inhibitor DAPT promoted early keratinocyte specification in human embryonic ...
Valerie Horsley, Lin Hou, Hongyu Zhao
exaly   +2 more sources

Ectoderm to mesoderm transition by down-regulation of actomyosin contractility

PLoS Biology, 2021
Collective migration of cohesive tissues is a fundamental process in morphogenesis and is particularly well illustrated during gastrulation by the rapid and massive internalization of the mesoderm, which contrasts with the much more modest movements of ...
François Fagotto, Paul Lasko, David Rozema   +2 more
exaly   +2 more sources

Distinct Requirements for Cranial Ectoderm and Mesenchyme-Derived Wnts in Specification and Differentiation of Osteoblast and Dermal Progenitors

PLoS Genetics, 2014
The cranial bones and dermis differentiate from mesenchyme beneath the surface ectoderm. Fate selection in cranial mesenchyme requires the canonical Wnt effector molecule β-catenin, but the relative contribution of Wnt ligand sources in this process ...
James Ferguson, Trevor Williams, Radhika P Atit   +2 more
exaly   +3 more sources

BMP-dependent patterning of ectoderm tissue material properties modulates lateral mesendoderm cell migration during early zebrafish gastrulation

Cell Reports
Summary: Cell migration is a fundamental process during embryonic development. Most studies in vivo have focused on the migration of cells using the extracellular matrix (ECM) as their substrate for migration.
David Brückner, Robert Hauschild, Carl-Philipp Heisenberg   +2 more
exaly   +3 more sources

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates [PDF]

PLoS Biology, 2017
During vertebrate neurulation, the embryonic ectoderm is patterned into lineage progenitors for neural plate, neural crest, placodes and epidermis.
Richard M Harland, Caroline Borday, Jean-Philippe Vert   +2 more
exaly   +2 more sources

Derivation and characteristics of induced pluripotent stem cells from a patient with acute myelitis

Frontiers in Cell and Developmental Biology, 2023
The emergence and development of induced pluripotent stem cells (iPSCs) provides an approach to understand the regulatory mechanisms of cell pluripotency and demonstrates the great potential of iPSCs in disease modeling. Acute myelitis defines a group of
Shuo Cao, Shuo Cao, Xinyue Gao, Xinyue Gao, Fangyuan Liu, Fangyuan Liu, Yanglin Chen, Yanglin Chen, Qin Na, Qin Na, Qin Na, Qiaoqiao Meng, Qiaoqiao Meng, Peng Shao, Peng Shao, Chen Chen, Chen Chen, Yongli Song, Yongli Song, Baojiang Wu, Baojiang Wu, Xihe Li, Xihe Li, Xihe Li, Siqin Bao, Siqin Bao   +25 more
doaj   +1 more source

Mature Mediastinal Teratoma [PDF]

Journal of Clinical and Diagnostic Research, 2015
A teratoma is a tumour with tissue or organ components resembling normal derivatives of more than one germ layer. We present a case of mediastinal mature teratoma as they have a low incidence rate.
Chikka Narasimhaiah Anushree, Vissa Shanti   +1 more
doaj   +1 more source

Feedback Regulation of Signaling Pathways for Precise Pre-Placodal Ectoderm Formation in Vertebrate Embryos

Journal of Developmental Biology, 2022
Intracellular signaling pathways are essential to establish embryonic patterning, including embryonic axis formation. Ectodermal patterning is also governed by a series of morphogens.
Tatsuo Michiue, Kohei Tsukano
doaj   +1 more source

AP-2α and AP-2β cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development

eLife, 2022
The facial surface ectoderm is essential for normal development of the underlying cranial neural crest cell populations, providing signals that direct appropriate growth, patterning, and morphogenesis.
Eric Van Otterloo, Isaac Milanda, Hamish Pike, Jamie A Thompson, Hong Li, Kenneth L Jones, Trevor Williams   +6 more
doaj   +1 more source